Mouse Models of Prostate Cancer
Joint Authors
Valkenburg, Kenneth C.
Williams, Bart O.
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-22, 22 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-02-23
Country of Publication
Egypt
No. of Pages
22
Main Subjects
Abstract EN
The development and optimization of high-throughput screening methods has identified a multitude of genetic changes associated with human disease.
The use of immunodeficient and genetically engineered mouse models that mimic the human disease has been crucial in validating the importance of these genetic pathways in prostate cancer.
These models provide a platform for finding novel therapies to treat human patients afflicted with prostate cancer as well as those who have debilitating bone metastases.
In this paper, we focus on the historical development and phenotypic descriptions of mouse models used to study prostate cancer.
We also comment on how closely each model recapitulates human prostate cancer.
American Psychological Association (APA)
Valkenburg, Kenneth C.& Williams, Bart O.. 2011. Mouse Models of Prostate Cancer. Prostate Cancer،Vol. 2011, no. 2011, pp.1-22.
https://search.emarefa.net/detail/BIM-506179
Modern Language Association (MLA)
Valkenburg, Kenneth C.& Williams, Bart O.. Mouse Models of Prostate Cancer. Prostate Cancer No. 2011 (2011), pp.1-22.
https://search.emarefa.net/detail/BIM-506179
American Medical Association (AMA)
Valkenburg, Kenneth C.& Williams, Bart O.. Mouse Models of Prostate Cancer. Prostate Cancer. 2011. Vol. 2011, no. 2011, pp.1-22.
https://search.emarefa.net/detail/BIM-506179
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-506179
