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Hypervolemia for Hypertension Pathophysiology : A Population-Based Study
Joint Authors
Büyükuysal, Çağatay
Köktürk, Füruzan
Özişik, Melih
Yildiz, Gürsel
Yildirim, İbrahim
Duman, Soner
Ateş, Kenan
Süleymanlar, Gültekin
Ural, Cihan
Budak Köse, Sennur
Hür, Ender
Mağden, Kemal
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-08-11
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Objectives.
Hypertension and hypervolemia relationship was proven among renal disease, although it is not known in normal population.
Present study determines the fluid distribution defects in relation to blood pressure.
Material and Methods.
In a population-based survey in Turkey demographics, height, weight, blood pressure, urine analysis, and serum creatinine measurements were recorded.
Bioimpedance measured with the Body Composition Monitor.
Results.
Total 2034 population of 71.6% male, mean age 47 ± 12.6 (18–89) years, systolic blood pressure (SBP) 134.7 ± 20, diastolic blood pressure 77.9 ± 11.6 mmHg.
Body mass index (BMI) was 28.5 ± 4.5 (15.8–50.6) kg/m2; overhydration was 0.05 ± 1.05 L.
There was a correlation between extracellular water (ECW)/height and SBP (r = 0.21, P < 0.001).
Receiver operating characteristic (ROC) curve with the performance of 0.60 (P < 0.001) that showed cut-off value of ECW/height was 10.06 L/m, with the 69% sensitivity and 45% specificity for SBP: 140 mmHg values.
Risk factors for high SBP were increase of ECW/Height, age, BMI and presence of diabetes.
ECW/height, SBP, and fat tissue index (FTI) increased in BMI categories (low, normal, and obese) and in diabetics.
SBP and FTI were lower in smokers.
Conclusions.
High blood pressure may be accompanied by increased extracellular volume indices.
In the future volume status assessment could be of use in evaluating the effectiveness of pharmacological intervention in the treatment of hypertension.
American Psychological Association (APA)
Hür, Ender& Özişik, Melih& Ural, Cihan& Yildiz, Gürsel& Mağden, Kemal& Budak Köse, Sennur…[et al.]. 2014. Hypervolemia for Hypertension Pathophysiology : A Population-Based Study. BioMed Research International،Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-506192
Modern Language Association (MLA)
Hür, Ender…[et al.]. Hypervolemia for Hypertension Pathophysiology : A Population-Based Study. BioMed Research International No. 2014 (2014), pp.1-9.
https://search.emarefa.net/detail/BIM-506192
American Medical Association (AMA)
Hür, Ender& Özişik, Melih& Ural, Cihan& Yildiz, Gürsel& Mağden, Kemal& Budak Köse, Sennur…[et al.]. Hypervolemia for Hypertension Pathophysiology : A Population-Based Study. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-506192
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-506192