Role of Scavenger Receptors in Glia-Mediated Neuroinflammatory Response Associated with Alzheimer’s Disease
Joint Authors
Cornejo, Francisca
von Bernhardi, Rommy
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-05-07
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
It is widely accepted that cells serving immune functions in the brain, namely, microglia and astrocytes, are important mediators of pathological phenomena observed in Alzheimer’s disease.
However, it is unknown how these cells initiate the response that results in cognitive impairment and neuronal degeneration.
Here, we review the participation of the immune response mediated by glial cells in Alzheimer’s disease and the role played by scavenger receptors in the development of this pathology, focusing on the relevance of class A scavenger receptor (SR-A) for Aβ clearance and inflammatory activation of glial cell, and as a potential target for Alzheimer’s disease therapy.
American Psychological Association (APA)
Cornejo, Francisca& von Bernhardi, Rommy. 2013. Role of Scavenger Receptors in Glia-Mediated Neuroinflammatory Response Associated with Alzheimer’s Disease. Mediators of Inflammation،Vol. 2013, no. 2013, pp.1-11.
https://search.emarefa.net/detail/BIM-506206
Modern Language Association (MLA)
Cornejo, Francisca& von Bernhardi, Rommy. Role of Scavenger Receptors in Glia-Mediated Neuroinflammatory Response Associated with Alzheimer’s Disease. Mediators of Inflammation No. 2013 (2013), pp.1-11.
https://search.emarefa.net/detail/BIM-506206
American Medical Association (AMA)
Cornejo, Francisca& von Bernhardi, Rommy. Role of Scavenger Receptors in Glia-Mediated Neuroinflammatory Response Associated with Alzheimer’s Disease. Mediators of Inflammation. 2013. Vol. 2013, no. 2013, pp.1-11.
https://search.emarefa.net/detail/BIM-506206
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-506206