![](/images/graphics-bg.png)
Mitochondria : Redox Metabolism and Dysfunction
Joint Authors
Source
Biochemistry Research International
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-14, 14 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-04-24
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Abstract EN
Mitochondria are the main intracellular location for fuel generation; however, they are not just power plants but involved in a range of other intracellular functions including regulation of redox homeostasis and cell fate.
Dysfunction of mitochondria will result in oxidative stress which is one of the underlying causal factors for a variety of diseases including neurodegenerative diseases, diabetes, cardiovascular diseases, and cancer.
In this paper, generation of reactive oxygen/nitrogen species (ROS/RNS) in the mitochondria, redox regulatory roles of certain mitochondrial proteins, and the impact on cell fate will be discussed.
The current state of our understanding in mitochondrial dysfunction in pathological states and how we could target them for therapeutic purpose will also be briefly reviewed.
American Psychological Association (APA)
Kang, Jia& Pervaiz, Shazib. 2012. Mitochondria : Redox Metabolism and Dysfunction. Biochemistry Research International،Vol. 2012, no. 2012, pp.1-14.
https://search.emarefa.net/detail/BIM-506306
Modern Language Association (MLA)
Kang, Jia& Pervaiz, Shazib. Mitochondria : Redox Metabolism and Dysfunction. Biochemistry Research International No. 2012 (2012), pp.1-14.
https://search.emarefa.net/detail/BIM-506306
American Medical Association (AMA)
Kang, Jia& Pervaiz, Shazib. Mitochondria : Redox Metabolism and Dysfunction. Biochemistry Research International. 2012. Vol. 2012, no. 2012, pp.1-14.
https://search.emarefa.net/detail/BIM-506306
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-506306