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Serotonin Syndrome after Sertraline Overdose in a Child : A Case Report
Joint Authors
Garrido, Ana
Brito, Hernani
Oliveira, Maria José
Santos, Fátima
Grenha, Joana
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-12-19
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
Serotonin syndrome is a potentially life-threatening drug effect.
It may be misdiagnosed because it has mostly been reported in adults.
Case Report.
An 8-year-old girl with behavioral problems and medicated with risperidone and sertraline was admitted in the emergency department after she had taken voluntarily 1500 mg of sertraline (50 mg/kg).
At admission, she had marked agitation, visual hallucinations, diaphoresis, flushing, and tremor.
She had fever and periods of hypertension.
She also showed generalized rigidity and involuntary movements.
She was treated with fluids and iv diazepam, midazolam, clemastine, and biperiden.
As the patient presented a severe insomnia and a progressive rhabdomyolysis, she was transferred to pediatric intensive care unit (ICU), where she was under treatment with cyproheptadine, mechanical ventilation, and muscular paralysis for 11 days.
She was discharged from hospital a few days later with no neurological sequelae.
Conclusions.
Serotonin syndrome is still not well recognized by physicians.
In our patient, the diagnosis was made early due to the history of overdose with serotonin reuptake inhibitors and the triad of mental, neurological, and autonomic signs.
Parents must be educated to prevent children from having free access to drugs, avoiding self-medication or overdose.
American Psychological Association (APA)
Grenha, Joana& Garrido, Ana& Brito, Hernani& Oliveira, Maria José& Santos, Fátima. 2013. Serotonin Syndrome after Sertraline Overdose in a Child : A Case Report. Case Reports in Pediatrics،Vol. 2013, no. 2013, pp.1-3.
https://search.emarefa.net/detail/BIM-506421
Modern Language Association (MLA)
Grenha, Joana…[et al.]. Serotonin Syndrome after Sertraline Overdose in a Child : A Case Report. Case Reports in Pediatrics No. 2013 (2013), pp.1-3.
https://search.emarefa.net/detail/BIM-506421
American Medical Association (AMA)
Grenha, Joana& Garrido, Ana& Brito, Hernani& Oliveira, Maria José& Santos, Fátima. Serotonin Syndrome after Sertraline Overdose in a Child : A Case Report. Case Reports in Pediatrics. 2013. Vol. 2013, no. 2013, pp.1-3.
https://search.emarefa.net/detail/BIM-506421
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-506421