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Switching to Aripiprazole as a Strategy for Weight Reduction : A Meta-Analysis in Patients Suffering from Schizophrenia
Joint Authors
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-08-25
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Weight gain is one of the major drawbacks associated with the pharmacological treatment of schizophrenia.
Existing strategies for the prevention and treatment of obesity amongst these patients are disappointing.
Switching the current antipsychotic to another that may favorably affect weight is not yet fully established in the psychiatric literature.
This meta-analysis focused on switching to aripiprazole as it has a pharmacological and clinical profile that may result in an improved weight control.
Nine publications from seven countries worldwide were analyzed.
These encompassed 784 schizophrenia and schizoaffective patients, 473 (60%) men and 311 (40%) women, mean age 39.4±7.0 years.
The major significant finding was a mean weight reduction by −2.55±1.5 kgs following the switch to aripiprazole (P<.001).
Switching to an antipsychotic with a lower propensity to induce weight gain needs be explored as a strategy.
Our analysis suggests aripiprazole as a candidate for such a treatment strategy.
American Psychological Association (APA)
Barak, Yoram& Aizenberg, Dov. 2010. Switching to Aripiprazole as a Strategy for Weight Reduction : A Meta-Analysis in Patients Suffering from Schizophrenia. Journal of Obesity،Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-506428
Modern Language Association (MLA)
Barak, Yoram& Aizenberg, Dov. Switching to Aripiprazole as a Strategy for Weight Reduction : A Meta-Analysis in Patients Suffering from Schizophrenia. Journal of Obesity No. 2011 (2011), pp.1-6.
https://search.emarefa.net/detail/BIM-506428
American Medical Association (AMA)
Barak, Yoram& Aizenberg, Dov. Switching to Aripiprazole as a Strategy for Weight Reduction : A Meta-Analysis in Patients Suffering from Schizophrenia. Journal of Obesity. 2010. Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-506428
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-506428