Metal-Based Biologically Active Compounds : Synthesis, Spectral, and Antimicrobial Studies of Cobalt, Nickel, Copper, and Zinc Complexes of Triazole-Derived Schiff Bases
Joint Authors
Sharma, Chetan
Aneja, Kamal Rai
Kumar, Yogender
Puri, Parvesh
Singh, Kiran
Source
Bioinorganic Chemistry and Applications
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-12-19
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
A series of cobalt, nickel, copper, and zinc complexes of bidentate Schiff bases derived from the condensation reaction of 4-amino-5-mercapto-3-methyl/ethyl-1,2,4-triazole with 2,4-dichlorobenzaldehyde were synthesized and tested as antimicrobial agents.
The synthesized Schiff bases and their metal complexes were characterized with the aid of elemental analyses, magnetic moment measurements, spectroscopic and thermogravimetric techniques.
The presence of coordinated water in metal complexes was supported by infrared and thermal gravimetric studies.
A square planar geometry was suggested for Cu(II) and octahedral geometry proposed for Co(II), Ni(II), and Zn(II) complexes.
The Schiff bases and their metal complexes have been screened for antibacterial (Pseudomonas aeruginosa, Bacillus subtilis) and antifungal activities (Aspergillus niger, A.
flavus).
The metal complexes exhibited significantly enhanced antibacterial and antifungal activity as compared to their simple Schiff bases.
American Psychological Association (APA)
Singh, Kiran& Kumar, Yogender& Puri, Parvesh& Sharma, Chetan& Aneja, Kamal Rai. 2011. Metal-Based Biologically Active Compounds : Synthesis, Spectral, and Antimicrobial Studies of Cobalt, Nickel, Copper, and Zinc Complexes of Triazole-Derived Schiff Bases. Bioinorganic Chemistry and Applications،Vol. 2011, no. 2011, pp.1-10.
https://search.emarefa.net/detail/BIM-506573
Modern Language Association (MLA)
Singh, Kiran…[et al.]. Metal-Based Biologically Active Compounds : Synthesis, Spectral, and Antimicrobial Studies of Cobalt, Nickel, Copper, and Zinc Complexes of Triazole-Derived Schiff Bases. Bioinorganic Chemistry and Applications No. 2011 (2011), pp.1-10.
https://search.emarefa.net/detail/BIM-506573
American Medical Association (AMA)
Singh, Kiran& Kumar, Yogender& Puri, Parvesh& Sharma, Chetan& Aneja, Kamal Rai. Metal-Based Biologically Active Compounds : Synthesis, Spectral, and Antimicrobial Studies of Cobalt, Nickel, Copper, and Zinc Complexes of Triazole-Derived Schiff Bases. Bioinorganic Chemistry and Applications. 2011. Vol. 2011, no. 2011, pp.1-10.
https://search.emarefa.net/detail/BIM-506573
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-506573
