An Efficient and Mild Method for the Synthesis and Hydrazinolysis of N-Glyoxylamino Acid Esters
Joint Authors
al-Marhoon, Zainab
Abdel-Megeed, Ahmed
El-Faham, Ayman
Siddiqui, M. Rafiq H.
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-11-21
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
N-Glyoxylamino acid ester derivatives were synthesized via the ring opening of N-acetylisatin using moderate conditions.
During the hydrazinolysis of N-glyoxylamino acid ester derivatives with hydrazine hydrate (80%) in methanol, unexpected reduction of the α-keto group occurred to afford N-acylamino acid hydrazide derivatives in good yield (80–90%) (Wolff-Kishner type reaction).
All the synthesized compounds were characterized by 1H NMR, 13C NMR, and elemental microanalysis.
American Psychological Association (APA)
El-Faham, Ayman& al-Marhoon, Zainab& Abdel-Megeed, Ahmed& Siddiqui, M. Rafiq H.. 2013. An Efficient and Mild Method for the Synthesis and Hydrazinolysis of N-Glyoxylamino Acid Esters. Journal of Chemistry،Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-506578
Modern Language Association (MLA)
El-Faham, Ayman…[et al.]. An Efficient and Mild Method for the Synthesis and Hydrazinolysis of N-Glyoxylamino Acid Esters. Journal of Chemistry No. 2013 (2013), pp.1-6.
https://search.emarefa.net/detail/BIM-506578
American Medical Association (AMA)
El-Faham, Ayman& al-Marhoon, Zainab& Abdel-Megeed, Ahmed& Siddiqui, M. Rafiq H.. An Efficient and Mild Method for the Synthesis and Hydrazinolysis of N-Glyoxylamino Acid Esters. Journal of Chemistry. 2013. Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-506578
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-506578