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Voltammetric Determination of Homocysteine Using Multiwall Carbon Nanotube Paste Electrode in the Presence of Chlorpromazine as a Mediator
Joint Authors
Fouladgar, Masoud
Karimi-Maleh, Hassan
Bagheri, Hasan
Beitollahi, Hadi
Gholami-Orimi, Fathali
Shamshiri, Mahmud
Taherkhani, Ali
Biparva, Pourya
Ebrahimi, Hamid R.
Taleshi, Farshad
Source
Journal of Analytical Methods in Chemistry
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-05-22
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
We propose chlorpromazine (CHP) as a new mediator for the rapid, sensitive, and highly selective voltammetric determination of homocysteine (Hcy) using multiwall carbon nanotube paste electrode (MWCNTPE).
The experimental results showed that the carbon nanotube paste electrode has a highly electrocatalytic activity for the oxidation of Hcy in the presence of CHP as a mediator.
Cyclic voltammetry, double potential step chronoamperometry, and square wave voltammetry (SWV) are used to investigate the suitability of CHP at the surface of MWCNTPE as a mediator for the electrocatalytic oxidation of Hcy in aqueous solutions.
The kinetic parameters of the system, including electron transfer coefficient, and catalytic rate constant were also determined using the electrochemical approaches.
In addition, SWV was used for quantitative analysis.
SWV showed wide linear dynamic range (0.1–210.0 μM Hcy) with a detection limit of 0.08 μM Hcy.
Finally, this method was also examined as a selective, simple, and precise electrochemical sensor for the determination of Hcy in real samples.
American Psychological Association (APA)
Gholami-Orimi, Fathali& Taleshi, Farshad& Biparva, Pourya& Karimi-Maleh, Hassan& Beitollahi, Hadi& Ebrahimi, Hamid R.…[et al.]. 2012. Voltammetric Determination of Homocysteine Using Multiwall Carbon Nanotube Paste Electrode in the Presence of Chlorpromazine as a Mediator. Journal of Analytical Methods in Chemistry،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-506620
Modern Language Association (MLA)
Gholami-Orimi, Fathali…[et al.]. Voltammetric Determination of Homocysteine Using Multiwall Carbon Nanotube Paste Electrode in the Presence of Chlorpromazine as a Mediator. Journal of Analytical Methods in Chemistry No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-506620
American Medical Association (AMA)
Gholami-Orimi, Fathali& Taleshi, Farshad& Biparva, Pourya& Karimi-Maleh, Hassan& Beitollahi, Hadi& Ebrahimi, Hamid R.…[et al.]. Voltammetric Determination of Homocysteine Using Multiwall Carbon Nanotube Paste Electrode in the Presence of Chlorpromazine as a Mediator. Journal of Analytical Methods in Chemistry. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-506620
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-506620