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A Clinical Study on Glucosamine Sulfate versus Combination of Glucosamine Sulfate and NSAIDs in Mild to Moderate Knee Osteoarthritis
Joint Authors
Nainar, M. Sundara-Moorthi
Rajiah, Kingston
Selvan, Tamil
Mathew, Elizabeth M.
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-04-01
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Medicine
Information Technology and Computer Science
Abstract EN
Background.
Glucosamine may be effective in treating and possibly slowing the progression of Osteoarthritis (OA).
It is believed Glucosamine supplements may help to stop cartilage breakdown, build cartilage and decrease swelling.
Objective.
The objective of this study was glucosamine sulfate versus combination of glucosamine sulfate and Non-Steroidal anti-inflammatory drugs (NSAID) in mild to moderate knee osteoarthritis.
Methods.
Subjects were randomly recruited from Rheumatology outpatient department after a diagnosis of mild or moderate Osteoarthritis.
Study tools like patient data collection form, Western Ontario McMaster Universities Arthritis index (WOMAC) of Osteoarthritis questionnaires and Visual Analog Scale (VAS) were used.
Results.
After 12 weeks, WOMAC total score the result showed that the significant mean difference between the group A and Group B treatment (P<0.01), with a combination of GS and NSAIDs reducing VAS pain scores.
Thus, it is found that Group B treatments over 4 and 12 weeks produced improved WOMAC and VAS grades.
Conclusions.
Study results may suggest that the Glucosamine Sulfate has a carryover effect like Disease modifying agents.
Long-term treatment of Glucosamine Sulfate may reduce the dependence of NSAIDs usage and delay the disease progression.
Thereby we can reduce the NSAIDs side effects and improve the patient's quality of life.
American Psychological Association (APA)
Selvan, Tamil& Rajiah, Kingston& Nainar, M. Sundara-Moorthi& Mathew, Elizabeth M.. 2012. A Clinical Study on Glucosamine Sulfate versus Combination of Glucosamine Sulfate and NSAIDs in Mild to Moderate Knee Osteoarthritis. The Scientific World Journal،Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-506662
Modern Language Association (MLA)
Selvan, Tamil…[et al.]. A Clinical Study on Glucosamine Sulfate versus Combination of Glucosamine Sulfate and NSAIDs in Mild to Moderate Knee Osteoarthritis. The Scientific World Journal No. 2012 (2012), pp.1-5.
https://search.emarefa.net/detail/BIM-506662
American Medical Association (AMA)
Selvan, Tamil& Rajiah, Kingston& Nainar, M. Sundara-Moorthi& Mathew, Elizabeth M.. A Clinical Study on Glucosamine Sulfate versus Combination of Glucosamine Sulfate and NSAIDs in Mild to Moderate Knee Osteoarthritis. The Scientific World Journal. 2012. Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-506662
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-506662