Curcumin and Other Polyphenolic Compounds in Head and Neck Cancer Chemoprevention
Joint Authors
Baumeister, Philipp
Harréus, Ulrich
Reiter, Maximilian
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-05-28
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Biology
Abstract EN
Despite clear results of observational studies linking a diet rich in fruits and vegetables to a decreased cancer risk, large interventional trials evaluating the impact of dietary micronutrient supplementation, mostly vitamins, could not show any beneficial effects.
Today it has become clear that a single micronutrient, given in supernutritional doses, cannot match cancer preventive effects of whole fruits and vegetables.
In this regard polyphenols came into focus, not only because of their antioxidant potential but also because of their ability to interact with molecular targets within the cells.
Because polyphenols occur in many foods and beverages in high concentration and evidence for their anticancer activity is best for tissues they can come into direct contact with, field cancerization predestines upper aerodigestive tract epithelium for cancer chemoprevention by polyphenols.
In this paper, we summarize cancer chemopreventive attempts with emphasis on head and neck carcinogenesis and discuss some methodological issues.
We present data regarding antimutagenic effects of curcumin and epigallocatechin-3-gallate in human oropharyngeal mucosa cultures exposed to cigarette smoke condensate.
American Psychological Association (APA)
Baumeister, Philipp& Reiter, Maximilian& Harréus, Ulrich. 2012. Curcumin and Other Polyphenolic Compounds in Head and Neck Cancer Chemoprevention. Oxidative Medicine and Cellular Longevity،Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-506669
Modern Language Association (MLA)
Baumeister, Philipp…[et al.]. Curcumin and Other Polyphenolic Compounds in Head and Neck Cancer Chemoprevention. Oxidative Medicine and Cellular Longevity No. 2012 (2012), pp.1-9.
https://search.emarefa.net/detail/BIM-506669
American Medical Association (AMA)
Baumeister, Philipp& Reiter, Maximilian& Harréus, Ulrich. Curcumin and Other Polyphenolic Compounds in Head and Neck Cancer Chemoprevention. Oxidative Medicine and Cellular Longevity. 2012. Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-506669
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-506669