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Atypical Squamous Cells of Undetermined Significance : Bethesda Classification and Association with Human Papillomavirus
Joint Authors
Adad, Sheila Jorge
Barcelos, Ana Cristina Macêdo
Michelin, Márcia Antoniazi
Murta, Eddie Fernando Candido
Source
Infectious Diseases in Obstetrics and Gynecology
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-06-29
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Introduction.
To analyze patients with atypical squamous cells of undetermined significance (ASCUS) through a cytology review and the presence of microbiological agents, with consideration of colposcopy and semiannual tracking.
Methods.
103 women with ASCUS were reviewed and reclassified: normal/inflammatory, ASCUS, low-grade squamous intraepithelial lesion (LSIL), or high-grade squamous intraepithelial lesion (HSIL).
If ASCUS confirmed, it was subclassified in reactive or neoplastic ASCUS, ASC-US, or ASC-H; and Regione Emilia Romagna Screening Protocol.
Patients underwent a colposcopic examination, and test for Candida sp., bacterial vaginosis, Trichomonas vaginalis, and human papillomavirus (HPV) were performed.
Results.
Upon review, ASCUS was diagnosis in 70/103 (67.9%), being 38 (54.2%) reactive ASCUS and 32 (45.71%) neoplastic ASCUS; 62 (88.5%) ASC-US and 8 (11.41%) ASC-H.
ASCUS (Regione Protocol), respectively 1-5: 15 (21.4%), 19 (27.1%), 3 (27.1%), 16 (22.8%), and 1 (1.4%).
A higher number of cases of cervical intraepithelial neoplasia (CIN) II/III in the biopsies of patients with ASC-H compared to ASC-US (P=.0021).
High-risk HPV test and presence of CIN II/III are more frequent in ASC-H than ASC-US (P=.031).
Conclusions.
ASC-H is associated with clinically significant disease.
High-risk HPV-positive status in the triage for colposcopy of patients with ASC-US is associated with increased of CIN.
American Psychological Association (APA)
Barcelos, Ana Cristina Macêdo& Michelin, Márcia Antoniazi& Adad, Sheila Jorge& Murta, Eddie Fernando Candido. 2011. Atypical Squamous Cells of Undetermined Significance : Bethesda Classification and Association with Human Papillomavirus. Infectious Diseases in Obstetrics and Gynecology،Vol. 2011, no. 2011, pp.1-9.
https://search.emarefa.net/detail/BIM-506847
Modern Language Association (MLA)
Barcelos, Ana Cristina Macêdo…[et al.]. Atypical Squamous Cells of Undetermined Significance : Bethesda Classification and Association with Human Papillomavirus. Infectious Diseases in Obstetrics and Gynecology No. 2011 (2011), pp.1-9.
https://search.emarefa.net/detail/BIM-506847
American Medical Association (AMA)
Barcelos, Ana Cristina Macêdo& Michelin, Márcia Antoniazi& Adad, Sheila Jorge& Murta, Eddie Fernando Candido. Atypical Squamous Cells of Undetermined Significance : Bethesda Classification and Association with Human Papillomavirus. Infectious Diseases in Obstetrics and Gynecology. 2011. Vol. 2011, no. 2011, pp.1-9.
https://search.emarefa.net/detail/BIM-506847
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-506847