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Cell-Specific Aptamers as Emerging Therapeutics
Joint Authors
Meyer, Cindy
Rentmeister, Andrea
Hahn, Ulrich
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-18, 18 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-08-28
Country of Publication
Egypt
No. of Pages
18
Main Subjects
Abstract EN
Aptamers are short nucleic acids that bind to defined targets with high affinity and specificity.
The first aptamers have been selected about two decades ago by an in vitro process named SELEX (systematic evolution of ligands by exponential enrichment).
Since then, numerous aptamers with specificities for a variety of targets from small molecules to proteins or even whole cells have been selected.
Their applications range from biosensing and diagnostics to therapy and target-oriented drug delivery.
More recently, selections using complex targets such as live cells have become feasible.
This paper summarizes progress in cell-SELEX techniques and highlights recent developments, particularly in the field of medically relevant aptamers with a focus on therapeutic and drug-delivery applications.
American Psychological Association (APA)
Meyer, Cindy& Hahn, Ulrich& Rentmeister, Andrea. 2011. Cell-Specific Aptamers as Emerging Therapeutics. Journal of Nucleic Acids،Vol. 2011, no. 2011, pp.1-18.
https://search.emarefa.net/detail/BIM-506860
Modern Language Association (MLA)
Meyer, Cindy…[et al.]. Cell-Specific Aptamers as Emerging Therapeutics. Journal of Nucleic Acids No. 2011 (2011), pp.1-18.
https://search.emarefa.net/detail/BIM-506860
American Medical Association (AMA)
Meyer, Cindy& Hahn, Ulrich& Rentmeister, Andrea. Cell-Specific Aptamers as Emerging Therapeutics. Journal of Nucleic Acids. 2011. Vol. 2011, no. 2011, pp.1-18.
https://search.emarefa.net/detail/BIM-506860
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-506860