![](/images/graphics-bg.png)
Rapid Synthesis of Superabsorbent Smart-Swelling Bacterial CelluloseAcrylamide-Based Hydrogels for Drug Delivery
Joint Authors
Abeer, Muhammad Mustafa
Navid Ahmad
Mohd Amin, Mohd Cairul Iqbal
Pandey, Manisha
Source
International Journal of Polymer Science
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-08-28
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
This study evaluated the effect of solubilized and dispersed bacterial cellulose (BC) on the physicochemical characteristics and drug release profile of hydrogels synthesized using biopolymers.
Superabsorbent hydrogels were synthesized by graft polymerization of acrylamide on BC solubilized in an NaOH/urea solvent system and on dispersed BC by using N,N′-methylenebisacrylamide as a crosslinker under microwave irradiation.
Fourier transform infrared spectroscopy analysis of the resulting hydrogels confirmed the grafting, and an X-ray diffraction pattern showed a decrease in the crystallinity of BC after the grafting process.
The hydrogels exhibited pH and ionic responsive swelling behavior, with hydrogels prepared using solubilized BC (SH) having higher swelling ratios.
Furthermore, compared to the hydrogels synthesized using dispersed BC, the hydrogels synthesized using solubilized BC showed higher porosity, drug loading efficiency, and release.
These results suggest the superiority of the hydrogels prepared using solubilized BC and that they should be explored further for oral drug delivery.
American Psychological Association (APA)
Pandey, Manisha& Mohd Amin, Mohd Cairul Iqbal& Navid Ahmad& Abeer, Muhammad Mustafa. 2013. Rapid Synthesis of Superabsorbent Smart-Swelling Bacterial CelluloseAcrylamide-Based Hydrogels for Drug Delivery. International Journal of Polymer Science،Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-506923
Modern Language Association (MLA)
Pandey, Manisha…[et al.]. Rapid Synthesis of Superabsorbent Smart-Swelling Bacterial CelluloseAcrylamide-Based Hydrogels for Drug Delivery. International Journal of Polymer Science No. 2013 (2013), pp.1-10.
https://search.emarefa.net/detail/BIM-506923
American Medical Association (AMA)
Pandey, Manisha& Mohd Amin, Mohd Cairul Iqbal& Navid Ahmad& Abeer, Muhammad Mustafa. Rapid Synthesis of Superabsorbent Smart-Swelling Bacterial CelluloseAcrylamide-Based Hydrogels for Drug Delivery. International Journal of Polymer Science. 2013. Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-506923
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-506923