Challenges for Biomarker Discovery in Body Fluids Using SELDI-TOF-MS
Joint Authors
Fillet, Marianne
Louis, Edouard
de Seny, Dominique
Meuwis, Marie-Alice
Chapelle, Jean-Paul
De Bock, Muriel
Merville, Marie-Paule
Malaise, Michel
Source
Journal of Biomedicine and Biotechnology
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-15, 15 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2009-12-06
Country of Publication
Egypt
No. of Pages
15
Main Subjects
Abstract EN
Protein profiling using SELDI-TOF-MS has gained over the past few years an increasing interest in the field of biomarker discovery.
The technology presents great potential if some parameters, such as sample handling, SELDI settings, and data analysis, are strictly controlled.
Practical considerations to set up a robust and sensitive strategy for biomarker discovery are presented.
This paper also reviews biological fluids generally available including a description of their peculiar properties and the preanalytical challenges inherent to sample collection and storage.
Finally, some new insights for biomarker identification and validation challenges are provided.
American Psychological Association (APA)
De Bock, Muriel& de Seny, Dominique& Meuwis, Marie-Alice& Chapelle, Jean-Paul& Louis, Edouard& Malaise, Michel…[et al.]. 2009. Challenges for Biomarker Discovery in Body Fluids Using SELDI-TOF-MS. Journal of Biomedicine and Biotechnology،Vol. 2010, no. 2010, pp.1-15.
https://search.emarefa.net/detail/BIM-506974
Modern Language Association (MLA)
De Bock, Muriel…[et al.]. Challenges for Biomarker Discovery in Body Fluids Using SELDI-TOF-MS. Journal of Biomedicine and Biotechnology No. 2010 (2010), pp.1-15.
https://search.emarefa.net/detail/BIM-506974
American Medical Association (AMA)
De Bock, Muriel& de Seny, Dominique& Meuwis, Marie-Alice& Chapelle, Jean-Paul& Louis, Edouard& Malaise, Michel…[et al.]. Challenges for Biomarker Discovery in Body Fluids Using SELDI-TOF-MS. Journal of Biomedicine and Biotechnology. 2009. Vol. 2010, no. 2010, pp.1-15.
https://search.emarefa.net/detail/BIM-506974
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-506974