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Starvation Ketoacidosis : A Cause of Severe Anion Gap Metabolic Acidosis in Pregnancy
Joint Authors
Venkatram, Sindhaghatta
Sinha, Nupur
Diaz-Fuentes, Gilda
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-05-20
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Pregnancy is a diabetogenic state characterized by relative insulin resistance, enhanced lipolysis, elevated free fatty acids and increased ketogenesis.
In this setting, short period of starvation can precipitate ketoacidosis.
This sequence of events is recognized as “accelerated starvation.” Metabolic acidosis during pregnancy may have adverse impact on fetal neural development including impaired intelligence and fetal demise.
Short periods of starvation during pregnancy may present as severe anion gap metabolic acidosis (AGMA).
We present a 41-year-old female in her 32nd week of pregnancy, admitted with severe AGMA with pH 7.16, anion gap 31, and bicarbonate of 5 mg/dL with normal lactate levels.
She was intubated and accepted to medical intensive care unit.
Urine and serum acetone were positive.
Evaluation for all causes of AGMA was negative.
The diagnosis of starvation ketoacidosis was established in absence of other causes of AGMA.
Intravenous fluids, dextrose, thiamine, and folic acid were administered with resolution of acidosis, early extubation, and subsequent normal delivery of a healthy baby at full term.
Rapid reversal of acidosis and favorable outcome are achieved with early administration of dextrose containing fluids.
American Psychological Association (APA)
Sinha, Nupur& Venkatram, Sindhaghatta& Diaz-Fuentes, Gilda. 2014. Starvation Ketoacidosis : A Cause of Severe Anion Gap Metabolic Acidosis in Pregnancy. Case Reports in Critical Care،Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-506999
Modern Language Association (MLA)
Sinha, Nupur…[et al.]. Starvation Ketoacidosis : A Cause of Severe Anion Gap Metabolic Acidosis in Pregnancy. Case Reports in Critical Care No. 2014 (2014), pp.1-4.
https://search.emarefa.net/detail/BIM-506999
American Medical Association (AMA)
Sinha, Nupur& Venkatram, Sindhaghatta& Diaz-Fuentes, Gilda. Starvation Ketoacidosis : A Cause of Severe Anion Gap Metabolic Acidosis in Pregnancy. Case Reports in Critical Care. 2014. Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-506999
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-506999