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Natural Killer Cells and Their Activation Status in Normal Pregnancy
Joint Authors
Nicolaides, Kypros H.
Wagner, Marion
Poon, Leona C. Y.
Shehata, Hassan
Ford, Brian
Mosimann, Beatrice
Bansal, Amolak S.
Source
International Journal of Reproductive Medicine
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-03-27
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Increased peripheral blood-activated NK cell counts are associated with increased risk of miscarriage and failed in vitro fertilization treatment.
However, assessment of activated peripheral NK cells in normal and pathological pregnancies beyond implantation and early miscarriage has not been described.
Total CD69 expressing NK cells counts were measured by flow cytometry in healthy women with singleton pregnancies, including 45 at 11+6–13+6 weeks’ gestation, 46 at 20+0–22+4 weeks, and 42 at 31+6–33+5 weeks.
The number of peripheral blood NK cells decreased, whereas the percentage of activated CD69 expressing NK cells increased from the first to the third trimester of pregnancy.
This study shows the course of peripheral blood NK cells and activated CD69 expressing NK cells in uncomplicated nulliparous singleton pregnancies.
This is a first step in understanding their implication in pathological pregnancies.
American Psychological Association (APA)
Mosimann, Beatrice& Wagner, Marion& Shehata, Hassan& Poon, Leona C. Y.& Ford, Brian& Nicolaides, Kypros H.…[et al.]. 2013. Natural Killer Cells and Their Activation Status in Normal Pregnancy. International Journal of Reproductive Medicine،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-507047
Modern Language Association (MLA)
Mosimann, Beatrice…[et al.]. Natural Killer Cells and Their Activation Status in Normal Pregnancy. International Journal of Reproductive Medicine No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-507047
American Medical Association (AMA)
Mosimann, Beatrice& Wagner, Marion& Shehata, Hassan& Poon, Leona C. Y.& Ford, Brian& Nicolaides, Kypros H.…[et al.]. Natural Killer Cells and Their Activation Status in Normal Pregnancy. International Journal of Reproductive Medicine. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-507047
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-507047