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Analyzing Coronary Artery Disease in Patients with Low CAC Scores by 64-Slice MDCT
Joint Authors
Chen, Tai-Been
Yeh, Lee-Ren
Lu, Nan-Han
Ding, Hueisch-Jy
Kuo, Chung-Ming
Huang, Yung-Hui
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-06-04
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Medicine
Information Technology and Computer Science
Abstract EN
Purpose.
Coronary artery calcification (CAC) scores are widely used to determine risk for Coronary Artery Disease (CAD).
A CAC score does not have the diagnostic accuracy needed for CAD.
This work uses a novel efficient approach to predict CAD in patients with low CAC scores.
Materials and Methods.
The study group comprised 86 subjects who underwent a screening health examination, including laboratory testing, CAC scanning, and cardiac angiography by 64-slice multidetector computed tomographic angiography.
Eleven physiological variables and three personal parameters were investigated in proposed model.
Logistic regression was applied to assess the sensitivity, specificity, and accuracy of when using individual variables and CAC score.
Meta-analysis combined physiological and personal parameters by logistic regression.
Results.
The diagnostic sensitivity of the CAC score was 14.3% when the CAC score was ≤30.
Sensitivity increased to 57.13% using the proposed model.
The statistically significant variables, based on beta values and P values, were family history, LDL-c, blood pressure, HDL-c, age, triglyceride, and cholesterol.
Conclusions.
The CAC score has low negative predictive value for CAD.
This work applied a novel prediction method that uses patient information, including physiological and society parameters.
The proposed method increases the accuracy of CAC score for predicting CAD.
American Psychological Association (APA)
Lu, Nan-Han& Yeh, Lee-Ren& Chen, Tai-Been& Huang, Yung-Hui& Kuo, Chung-Ming& Ding, Hueisch-Jy. 2012. Analyzing Coronary Artery Disease in Patients with Low CAC Scores by 64-Slice MDCT. The Scientific World Journal،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-507083
Modern Language Association (MLA)
Lu, Nan-Han…[et al.]. Analyzing Coronary Artery Disease in Patients with Low CAC Scores by 64-Slice MDCT. The Scientific World Journal No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-507083
American Medical Association (AMA)
Lu, Nan-Han& Yeh, Lee-Ren& Chen, Tai-Been& Huang, Yung-Hui& Kuo, Chung-Ming& Ding, Hueisch-Jy. Analyzing Coronary Artery Disease in Patients with Low CAC Scores by 64-Slice MDCT. The Scientific World Journal. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-507083
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-507083