Multimodal MRI Neuroimaging Biomarkers for Cognitive Normal Adults, Amnestic Mild Cognitive Impairment, and Alzheimer's Disease
Joint Authors
Gao, Jia-Hong
Fox, Peter T.
Lin, Ai-Ling
Laird, Angela R.
Source
Neurology Research International
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-17, 17 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-09-21
Country of Publication
Egypt
No. of Pages
17
Main Subjects
Abstract EN
Multimodal magnetic resonance imaging (MRI) techniques have been developed to noninvasively measure structural, metabolic, hemodynamic and functional changes of the brain.
These advantages have made MRI an important tool to investigate neurodegenerative disorders, including diagnosis, disease progression monitoring, and treatment efficacy evaluation.
This paper discusses recent findings of the multimodal MRI in the context of surrogate biomarkers for identifying the risk for AD in normal cognitive (NC) adults, brain anatomical and functional alterations in amnestic mild cognitive impairment (aMCI), and Alzheimer's disease (AD) patients.
Further developments of these techniques and the establishment of promising neuroimaging biomarkers will enhance our ability to diagnose aMCI and AD in their early stages and improve the assessment of therapeutic efficacy in these diseases in future clinical trials.
American Psychological Association (APA)
Lin, Ai-Ling& Laird, Angela R.& Fox, Peter T.& Gao, Jia-Hong. 2011. Multimodal MRI Neuroimaging Biomarkers for Cognitive Normal Adults, Amnestic Mild Cognitive Impairment, and Alzheimer's Disease. Neurology Research International،Vol. 2012, no. 2012, pp.1-17.
https://search.emarefa.net/detail/BIM-507131
Modern Language Association (MLA)
Lin, Ai-Ling…[et al.]. Multimodal MRI Neuroimaging Biomarkers for Cognitive Normal Adults, Amnestic Mild Cognitive Impairment, and Alzheimer's Disease. Neurology Research International No. 2012 (2012), pp.1-17.
https://search.emarefa.net/detail/BIM-507131
American Medical Association (AMA)
Lin, Ai-Ling& Laird, Angela R.& Fox, Peter T.& Gao, Jia-Hong. Multimodal MRI Neuroimaging Biomarkers for Cognitive Normal Adults, Amnestic Mild Cognitive Impairment, and Alzheimer's Disease. Neurology Research International. 2011. Vol. 2012, no. 2012, pp.1-17.
https://search.emarefa.net/detail/BIM-507131
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-507131