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Nebulized Pentamidine-Induced Acute Renal Allograft Dysfunction
Joint Authors
Prabhavalkar, Siddhesh
Masengu, Agnes
O'Rourke, Declan
Courtney, Aisling
Shields, Joanne
Source
Case Reports in Transplantation
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-01-17
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
Acute kidney injury (AKI) is a recognised complication of intravenous pentamidine therapy.
A direct nephrotoxic effect leading to acute tubular necrosis has been postulated.
We report a case of severe renal allograft dysfunction due to nebulised pentamidine.
The patient presented with repeated episodes of AKI without obvious cause and acute tubular necrosis only on renal histology.
Nebulised pentamidine was used monthly as prophylaxis for Pneumocystis jirovecii pneumonia, and administration preceded the creatinine rise on each occasion.
Graft function stabilised following discontinuation of the drug.
This is the first report of nebulized pentamidine-induced reversible nephrotoxicity in a kidney allograft.
This diagnosis should be considered in a case of unexplained acute renal allograft dysfunction.
American Psychological Association (APA)
Prabhavalkar, Siddhesh& Masengu, Agnes& O'Rourke, Declan& Shields, Joanne& Courtney, Aisling. 2013. Nebulized Pentamidine-Induced Acute Renal Allograft Dysfunction. Case Reports in Transplantation،Vol. 2013, no. 2013, pp.1-3.
https://search.emarefa.net/detail/BIM-507154
Modern Language Association (MLA)
Prabhavalkar, Siddhesh…[et al.]. Nebulized Pentamidine-Induced Acute Renal Allograft Dysfunction. Case Reports in Transplantation No. 2013 (2013), pp.1-3.
https://search.emarefa.net/detail/BIM-507154
American Medical Association (AMA)
Prabhavalkar, Siddhesh& Masengu, Agnes& O'Rourke, Declan& Shields, Joanne& Courtney, Aisling. Nebulized Pentamidine-Induced Acute Renal Allograft Dysfunction. Case Reports in Transplantation. 2013. Vol. 2013, no. 2013, pp.1-3.
https://search.emarefa.net/detail/BIM-507154
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-507154