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New Pathways for Alimentary Mucositis
Joint Authors
Bowen, Joanne M.
Keefe, Dorothy M. K.
Source
Issue
Vol. 2008, Issue 2008 (31 Dec. 2008), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2008-09-23
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Alimentary mucositis is a major dose-limiting toxicity associated with anticancer treatment.
It is responsible for reducing patient quality of life and represents a significant economic burden in oncology.
The pathobiology of alimentary mucositis is extremely complex, and an increased understanding of mechanisms and pathway interactions is required to rationally design improved therapies.
This review describes the latest advances in defining mechanisms of alimentary mucositis pathobiology in the context of pathway activation.
It focuses particularly on the recent genome-wide analyses of regimen-related mucosal injury and the identification of specific regulatory pathways implicated in mucositis development.
This review also discusses the currently known alimentary mucositis risk factors and the development of novel treatments.
Suggestions for future research directions have been raised.
American Psychological Association (APA)
Bowen, Joanne M.& Keefe, Dorothy M. K.. 2008. New Pathways for Alimentary Mucositis. Journal of Oncology،Vol. 2008, no. 2008, pp.1-7.
https://search.emarefa.net/detail/BIM-507170
Modern Language Association (MLA)
Bowen, Joanne M.& Keefe, Dorothy M. K.. New Pathways for Alimentary Mucositis. Journal of Oncology No. 2008 (2008), pp.1-7.
https://search.emarefa.net/detail/BIM-507170
American Medical Association (AMA)
Bowen, Joanne M.& Keefe, Dorothy M. K.. New Pathways for Alimentary Mucositis. Journal of Oncology. 2008. Vol. 2008, no. 2008, pp.1-7.
https://search.emarefa.net/detail/BIM-507170
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-507170