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Performance of BVBlue Rapid Test in Detecting Bacterial Vaginosis among Women in Mysore, India
Joint Authors
Li, Tan
Ravi, Kavitha
Klausner, Jeffrey D.
Srinivas, Vijaya
Arun, Anjali
Krupp, Karl
Selezneva, Julia
Madhivanan, Purnima
Source
Infectious Diseases in Obstetrics and Gynecology
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-01-12
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Bacterial vaginosis (BV) is the most common cause of abnormal vaginal discharge in reproductive age women.
It is associated with increased susceptibility to HIV/STI and adverse birth outcomes.
Diagnosis of BV in resource-poor settings like India is challenging.
With little laboratory infrastructure there is a need for objective point-of-care diagnostic tests.
Vaginal swabs were collected from women 18 years and older, with a vaginal pH > 4.5 attending a reproductive health clinic.
BV was diagnosed with Amsel’s criteria, Nugent scores, and the OSOM BVBlue test.
Study personnel were blinded to test results.
There were 347 participants enrolled between August 2009 and January 2010.
BV prevalence was 45.1% (95% confidence interval (CI): 41.5%–52.8%) according to Nugent score.
When compared with Nugent score, the sensitivity, specificity, positive predictive value, negative predictive value for Amsel’s criteria and BVBlue were 61.9%, 88.3%, 81.5%, 73.7% and 38.1%, 92.7%, 82.1%, 63.9%, respectively.
Combined with a “whiff” test, the performance of BVBlue increased sensitivity to 64.4% and negative predictive value to 73.8%.
Despite the good specificity, poor sensitivity limits the usefulness of the BVBlue as a screening test in this population.
There is a need to examine the usefulness of this test in other Indian populations.
American Psychological Association (APA)
Madhivanan, Purnima& Krupp, Karl& Li, Tan& Ravi, Kavitha& Selezneva, Julia& Srinivas, Vijaya…[et al.]. 2014. Performance of BVBlue Rapid Test in Detecting Bacterial Vaginosis among Women in Mysore, India. Infectious Diseases in Obstetrics and Gynecology،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-507215
Modern Language Association (MLA)
Madhivanan, Purnima…[et al.]. Performance of BVBlue Rapid Test in Detecting Bacterial Vaginosis among Women in Mysore, India. Infectious Diseases in Obstetrics and Gynecology No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-507215
American Medical Association (AMA)
Madhivanan, Purnima& Krupp, Karl& Li, Tan& Ravi, Kavitha& Selezneva, Julia& Srinivas, Vijaya…[et al.]. Performance of BVBlue Rapid Test in Detecting Bacterial Vaginosis among Women in Mysore, India. Infectious Diseases in Obstetrics and Gynecology. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-507215
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-507215