Synthesis of Novel 1,2,4-Triazole Derivatives as Antimicrobial Agents via the Japp-Klingemann Reaction : Investigation of Antimicrobial Activities

Joint Authors

Dorababu, Atukuri
Meti, Gangadhar Y.
Taj, Tasneem
Kamble, Ravindra R.

Source

Journal of Chemistry

Issue

Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-9, 9 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2013-09-18

Country of Publication

Egypt

No. of Pages

9

Main Subjects

Chemistry

Abstract EN

In the present investigation, 1,2,4-triazole appended to pyrazoline and pyrazole rings (4a–g) using N-arylsydnone as synthon was prepared.

The title compounds were subjected to Osiris property explorer for the oral bioavailability to analyze their drug likeness and drug score.

Further, the compounds were subjected to the antimicrobial activity and analyzed the IC 50 and MIC values.

American Psychological Association (APA)

Taj, Tasneem& Kamble, Ravindra R.& Dorababu, Atukuri& Meti, Gangadhar Y.. 2013. Synthesis of Novel 1,2,4-Triazole Derivatives as Antimicrobial Agents via the Japp-Klingemann Reaction : Investigation of Antimicrobial Activities. Journal of Chemistry،Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-507343

Modern Language Association (MLA)

Taj, Tasneem…[et al.]. Synthesis of Novel 1,2,4-Triazole Derivatives as Antimicrobial Agents via the Japp-Klingemann Reaction : Investigation of Antimicrobial Activities. Journal of Chemistry No. 2013 (2013), pp.1-9.
https://search.emarefa.net/detail/BIM-507343

American Medical Association (AMA)

Taj, Tasneem& Kamble, Ravindra R.& Dorababu, Atukuri& Meti, Gangadhar Y.. Synthesis of Novel 1,2,4-Triazole Derivatives as Antimicrobial Agents via the Japp-Klingemann Reaction : Investigation of Antimicrobial Activities. Journal of Chemistry. 2013. Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-507343

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-507343