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Antimicrobial Peptides in Gastrointestinal Inflammation
Joint Authors
Jäger, Simon
Stange, Eduard F.
Wehkamp, Jan
Source
International Journal of Inflammation
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-11-25
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Acute and chronic inflammations of mucosal surfaces are complex events in which the effector mechanisms of innate and adaptive immune systems interact with pathogenic and commensal bacteria.
The role of constitutive and inducible antimicrobial peptides in intestinal inflammation has been investigated thoroughly over the recent years, and their involvement in various disease states is expanded ever more.
Especially in the intestines, a critical balance between luminal bacteria and the antimicrobial peptides is essential, and a breakdown in barrier function by impaired production of defensins is already implicated in Crohn's disease.
In this paper, we focus on the role of antimicrobial peptides in inflammatory processes along the gastrointestinal tract, while considering the resident and pathogenic flora encountered at the specific sites.
The role of antimicrobial peptides in the primary events of inflammatory bowel diseases receives special attention.
American Psychological Association (APA)
Jäger, Simon& Stange, Eduard F.& Wehkamp, Jan. 2010. Antimicrobial Peptides in Gastrointestinal Inflammation. International Journal of Inflammation،Vol. 2010, no. 2010, pp.1-11.
https://search.emarefa.net/detail/BIM-507375
Modern Language Association (MLA)
Jäger, Simon…[et al.]. Antimicrobial Peptides in Gastrointestinal Inflammation. International Journal of Inflammation No. 2010 (2010), pp.1-11.
https://search.emarefa.net/detail/BIM-507375
American Medical Association (AMA)
Jäger, Simon& Stange, Eduard F.& Wehkamp, Jan. Antimicrobial Peptides in Gastrointestinal Inflammation. International Journal of Inflammation. 2010. Vol. 2010, no. 2010, pp.1-11.
https://search.emarefa.net/detail/BIM-507375
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-507375