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Immunologic Monitoring of Cellular Responses by DendriticTumor Cell Fusion Vaccines
Joint Authors
Nagatsuma, Keisuke
Homma, Sadamu
Koido, Shigeo
Nagasaki, Eijiro
Namiki, Yoshihisa
Ito, Masaki
Satoh, Kenichi
Takahara, Akitaka
Ohkusa, Toshifumi
Komita, Hideo
Gong, Jianlin
Tajiri, Hisao
Uchiyama, Kan
Source
Journal of Biomedicine and Biotechnology
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-04-26
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
Although dendritic cell (DC)- based cancer vaccines induce effective antitumor activities in murine models, only limited therapeutic results have been obtained in clinical trials.
As cancer vaccines induce antitumor activities by eliciting or modifying immune responses in patients with cancer, the Response Evaluation Criteria in Solid Tumors (RECIST) and WHO criteria, designed to detect early effects of cytotoxic chemotherapy in solid tumors, may not provide a complete assessment of cancer vaccines.
The problem may, in part, be resolved by carrying out immunologic cellular monitoring, which is one prerequisite for rational development of cancer vaccines.
In this review, we will discuss immunologic monitoring of cellular responses for the evaluation of cancer vaccines including fusions of DC and whole tumor cell.
American Psychological Association (APA)
Koido, Shigeo& Homma, Sadamu& Takahara, Akitaka& Namiki, Yoshihisa& Komita, Hideo& Nagasaki, Eijiro…[et al.]. 2011. Immunologic Monitoring of Cellular Responses by DendriticTumor Cell Fusion Vaccines. Journal of Biomedicine and Biotechnology،Vol. 2011, no. 2011, pp.1-13.
https://search.emarefa.net/detail/BIM-507435
Modern Language Association (MLA)
Koido, Shigeo…[et al.]. Immunologic Monitoring of Cellular Responses by DendriticTumor Cell Fusion Vaccines. Journal of Biomedicine and Biotechnology No. 2011 (2011), pp.1-13.
https://search.emarefa.net/detail/BIM-507435
American Medical Association (AMA)
Koido, Shigeo& Homma, Sadamu& Takahara, Akitaka& Namiki, Yoshihisa& Komita, Hideo& Nagasaki, Eijiro…[et al.]. Immunologic Monitoring of Cellular Responses by DendriticTumor Cell Fusion Vaccines. Journal of Biomedicine and Biotechnology. 2011. Vol. 2011, no. 2011, pp.1-13.
https://search.emarefa.net/detail/BIM-507435
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-507435