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Safety and Efficacy of Radiofrequency Ablation in the Management of Unresectable Bile Duct and Pancreatic Cancer : A Novel Palliation Technique
Joint Authors
Millman, Jennifer
Gaidhane, Monica R.
Ellen, Kristi
Habib, Nagy A.
Kahaleh, Michel
Bakhru, Mihir R.
Figueroa-Barojas, Paola
Jamal-Kabani, Armeen
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-04-08
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Objectives.
Radiofrequency ablation (RFA) has replaced photodynamic therapy for premalignant and malignant lesions of the esophagus.
However, there is limited experience in the bile duct.
The objective of this pilot study was to assess the safety and efficacy of RFA in malignant biliary strictures.
Methods: Twenty patients with unresectable malignant biliary strictures underwent RFA with stenting between June 2010 and July 2012.
Diameters of the stricture before and after RFA, immediate and 30 day complications and stent patency were recorded prospectively.
Results.
A total of 25 strictures were treated.
Mean stricture length treated was 15.2 mm (SD = 8.7 mm, Range = 3.5–33 mm).
Mean stricture diameter before RFA was 1.7 mm (SD = 0.9 mm, Range = 0.5–3.4 mm) while the mean diameter after RFA was 5.2 mm (SD = 2 mm, Range = 2.6–9 mm).
There was a significant increase of 3.5 mm (t = 10.8, DF = 24, P value = <.0001) in the bile duct diameter post RFA.
Five patients presented with pain after the procedure, but only one developed mild post-ERCP pancreatitis and cholecystitis.
Conclusions: Radiofrequency ablation can be a safe palliation option for unresectable malignant biliary strictures.
A multicenter randomized controlled trial is required to confirm the long term benefits of RFA and stenting compared to stenting alone.
American Psychological Association (APA)
Figueroa-Barojas, Paola& Bakhru, Mihir R.& Habib, Nagy A.& Ellen, Kristi& Millman, Jennifer& Jamal-Kabani, Armeen…[et al.]. 2013. Safety and Efficacy of Radiofrequency Ablation in the Management of Unresectable Bile Duct and Pancreatic Cancer : A Novel Palliation Technique. Journal of Oncology،Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-507442
Modern Language Association (MLA)
Figueroa-Barojas, Paola…[et al.]. Safety and Efficacy of Radiofrequency Ablation in the Management of Unresectable Bile Duct and Pancreatic Cancer : A Novel Palliation Technique. Journal of Oncology No. 2013 (2013), pp.1-5.
https://search.emarefa.net/detail/BIM-507442
American Medical Association (AMA)
Figueroa-Barojas, Paola& Bakhru, Mihir R.& Habib, Nagy A.& Ellen, Kristi& Millman, Jennifer& Jamal-Kabani, Armeen…[et al.]. Safety and Efficacy of Radiofrequency Ablation in the Management of Unresectable Bile Duct and Pancreatic Cancer : A Novel Palliation Technique. Journal of Oncology. 2013. Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-507442
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-507442