Predictors of Cognitive Decline in the Early Stages of Parkinson's Disease : A Brief Cognitive Assessment Longitudinal Study
Joint Authors
Viana-Baptista, Miguel
Bugalho, Paulo
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-11-05
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Our objectives were to perform a longitudinal assessment of mental status in early stage Parkinson’s disease (PD) patients, with brief neuropsychological tests, in order to find predictive factors for cognitive decline.
Sixty-one, early stage, and nondemented patients were assessed twice, over a 2-year interval, with a global cognitive test (mini-mental state examination (MMSE)) and a frontal function test (frontal assessment battery (FAB)) and motor function scales.
Dementia and hallucinations were diagnosed according to the DSM-IV criteria.
Cognitive function scores did not decrease significantly, except for FAB lexical fluency score.
Four patients presented with dementia at followup.
The MMSE score below cut-off, worse gait dysfunction, the nontremor motor subtype, and hallucinations were significantly related to dementia.
Rigidity and speech dysfunction were related to dementia and a decrease in FAB scores.
We can conclude that decline in the MMSE and FAB scores is small and heterogeneous in the early stages of PD.
Scores below cut-off in the MMSE could be helpful to predict dementia.
Nontremor motor deficits could be predictive factors for frontal cognitive decline and dementia.
American Psychological Association (APA)
Bugalho, Paulo& Viana-Baptista, Miguel. 2013. Predictors of Cognitive Decline in the Early Stages of Parkinson's Disease : A Brief Cognitive Assessment Longitudinal Study. Evidence-Based Complementary and Alternative Medicine،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-507458
Modern Language Association (MLA)
Bugalho, Paulo& Viana-Baptista, Miguel. Predictors of Cognitive Decline in the Early Stages of Parkinson's Disease : A Brief Cognitive Assessment Longitudinal Study. Evidence-Based Complementary and Alternative Medicine No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-507458
American Medical Association (AMA)
Bugalho, Paulo& Viana-Baptista, Miguel. Predictors of Cognitive Decline in the Early Stages of Parkinson's Disease : A Brief Cognitive Assessment Longitudinal Study. Evidence-Based Complementary and Alternative Medicine. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-507458
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-507458