The Treatment of Peritoneal Carcinomatosis in Advanced Gastric Cancer : State of the Art
Joint Authors
Poletti, Eugenio
Colaianni, Nicola
Ceresoli, Marco
Coccolini, Federico
Montori, Giulia
Ansaloni, Luca
Catena, Fausto
Source
International Journal of Surgical Oncology
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-02-17
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Gastric cancer (GC) is the fourth most common cancer and the second leading cause of cancer death in the world; 53–60% of patients show disease progression and die of peritoneal carcinomatosis (PC).
PC of gastric origin has an extremely inauspicious prognosis with a median survival estimate at 1–3 months.
Different studies presented contrasting data about survival rates; however, all agreed with the necessity of a complete cytoreduction to improve survival.
Hyperthermic intraperitoneal chemotherapy (HIPEC) has an adjuvant role in preventing peritoneal recurrences.
A multidisciplinary approach should be empowered: the association of neoadjuvant intraperitoneal and systemic chemotherapy (NIPS), cytoreductive surgery (CRS), HIPEC, and early postoperative intraperitoneal chemotherapy (EPIC) could increase the rate of completeness of cytoreduction (CC) and consequently survival rates, especially in patients with Peritoneal Cancer Index (PCI) ≤6.
Neoadjuvant chemotherapy may improve survival also in PC from GC and adjuvant chemotherapy could prevent recurrence.
In the last decade an interesting new drug, called Catumaxomab, has been developed in Germany.
Two studies showed that this drug seems to improve progression-free survival in patients with GC; however, final results for both studies have still to be published.
American Psychological Association (APA)
Montori, Giulia& Coccolini, Federico& Ceresoli, Marco& Catena, Fausto& Colaianni, Nicola& Poletti, Eugenio…[et al.]. 2014. The Treatment of Peritoneal Carcinomatosis in Advanced Gastric Cancer : State of the Art. International Journal of Surgical Oncology،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-507488
Modern Language Association (MLA)
Montori, Giulia…[et al.]. The Treatment of Peritoneal Carcinomatosis in Advanced Gastric Cancer : State of the Art. International Journal of Surgical Oncology No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-507488
American Medical Association (AMA)
Montori, Giulia& Coccolini, Federico& Ceresoli, Marco& Catena, Fausto& Colaianni, Nicola& Poletti, Eugenio…[et al.]. The Treatment of Peritoneal Carcinomatosis in Advanced Gastric Cancer : State of the Art. International Journal of Surgical Oncology. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-507488
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-507488