Evaluation of Granulocyte Colony-Stimulating Factor Effects on Treatment-Resistant Thin Endometrium in Women Undergoing In Vitro Fertilization
Joint Authors
Liss, Joanna
Łukaszuk, Krzysztof
Kunicki, Michał
Szczyptańska, Joanna
Wocławek-Potocka, Izabela
Kulwikowska, Patrycja
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-02-12
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
The aim of the study was to assess the granulocyte colony-stimulating factor (G-CSF) effects on unresponsive thin (<7 mm) endometrium in women undergoing in vitro fertilization (IVF).
We included thirty-seven subjects who had thin unresponsive endometrium on the day of triggering ovulation.
These patients also failed to achieve an adequate endometrial thickness in at least one of their previous IVF cycles.
In all the subjects at the time of infusion of G-CSF, endometrial thickness was 6,74 ± 1,75 mm, and, after infusion, it increased significantly to 8,42 ± 1,73 mm.
When we divided the group into two subgroups according to whether the examined women conceived, we showed that the endometrium expanded significantly from 6,86 ± 1,65 to 8,80 ± 1,14 mm in the first group (who conceived) and from 6,71 ± 1,80 to 8,33 ± 1,85 mm in the second, respectively.
There were no significant differences between the two subgroups in respect to the endometrial thickness both before and after G-CSF infusion.
The clinical pregnancy rate was 18,9%.
We concluded that the infusion of G-CSF leads to the improvement of endometrium thickness after 72 hours.
American Psychological Association (APA)
Kunicki, Michał& Łukaszuk, Krzysztof& Wocławek-Potocka, Izabela& Liss, Joanna& Kulwikowska, Patrycja& Szczyptańska, Joanna. 2014. Evaluation of Granulocyte Colony-Stimulating Factor Effects on Treatment-Resistant Thin Endometrium in Women Undergoing In Vitro Fertilization. BioMed Research International،Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-507576
Modern Language Association (MLA)
Kunicki, Michał…[et al.]. Evaluation of Granulocyte Colony-Stimulating Factor Effects on Treatment-Resistant Thin Endometrium in Women Undergoing In Vitro Fertilization. BioMed Research International No. 2014 (2014), pp.1-5.
https://search.emarefa.net/detail/BIM-507576
American Medical Association (AMA)
Kunicki, Michał& Łukaszuk, Krzysztof& Wocławek-Potocka, Izabela& Liss, Joanna& Kulwikowska, Patrycja& Szczyptańska, Joanna. Evaluation of Granulocyte Colony-Stimulating Factor Effects on Treatment-Resistant Thin Endometrium in Women Undergoing In Vitro Fertilization. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-507576
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-507576