Evaluation of Corneal Endothelium in Children and Adolescents with Type 1 Diabetes Mellitus
Joint Authors
Urban, Beata
Raczyńska, Krystyna
Bakunowicz-Łazarczyk, Alina
Raczyńska, Dorota
Krętowska, Małgorzata
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-12-08
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Purpose.
To evaluate the systemic and local factors that contribute to the damage of endothelial cells in diabetic patients and to compare the endothelial structure of the cornea in diabetic and nondiabetic patients.
Materials and Methods.
The endothelial cell density (ECD) and central corneal thickness (CCT) were investigated in 123 eyes of type 1 diabetic patients and in 124 eyes of nondiabetic patients.
The mean diabetic patients age was 15.34 ± 3.06 years versus 14.58 ± 2.01 years in the control group.
The mean duration of diabetes was 8.02 ± 3.9 years.
The corneal endothelium was imaged by the Topcon SP-2000P.
Results.
The mean ECD in diabetic eyes was 2435.55 ± 443.43 cells/mm2 and was significantly lower than in control group (2970.75 ± 270.1 cells/mm2).
The mean CCT was 0.55 ± 0.03 mm in diabetic group versus 0.53 ± 0.033 mm in control group.
ECD and CCT significantly correlated only with duration of diabetes.
There was no correlation between ECD and CCT and patient age, sex, HbA1C level, and plasma creatinine level.
Conclusions.
ECD is decreased and CCT is increased in children and adolescents with diabetes mellitus.
Duration of diabetes is the factor that affects ECD and CCT.
American Psychological Association (APA)
Urban, Beata& Raczyńska, Dorota& Bakunowicz-Łazarczyk, Alina& Raczyńska, Krystyna& Krętowska, Małgorzata. 2013. Evaluation of Corneal Endothelium in Children and Adolescents with Type 1 Diabetes Mellitus. Mediators of Inflammation،Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-507614
Modern Language Association (MLA)
Urban, Beata…[et al.]. Evaluation of Corneal Endothelium in Children and Adolescents with Type 1 Diabetes Mellitus. Mediators of Inflammation No. 2013 (2013), pp.1-6.
https://search.emarefa.net/detail/BIM-507614
American Medical Association (AMA)
Urban, Beata& Raczyńska, Dorota& Bakunowicz-Łazarczyk, Alina& Raczyńska, Krystyna& Krętowska, Małgorzata. Evaluation of Corneal Endothelium in Children and Adolescents with Type 1 Diabetes Mellitus. Mediators of Inflammation. 2013. Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-507614
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-507614