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Synthesis, Characterization, Antibacterial and Anti-Inflammatory Activities of Enoxacin Metal Complexes
Joint Authors
Sultana, Najma
Mesaik, M. Ahmed
Arayne, Saeed
Haroon, Urooj
Source
Bioinorganic Chemistry and Applications
Issue
Vol. 2009, Issue 2009 (31 Dec. 2009), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2009-08-02
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
The present work comprises the synthesis of enoxacin (Heno) complexes with various transition metals.
Two types of complexes [M(eno)2(H2O)2]3H2O(M=CuII, NiII or MnII) and [M(eno)(H2O)2]Cl⋅4H2O (M=FeIII) were obtained.
The complexes were characterized by different physicochemical, spectroscopic, and elemental analysis.
Results suggest that enoxacin interacts with the metals as a monoanionic bidentate ligand.
These complexes were also tested for their antibacterial activity against eleven (11) different microorganisms, and the results were compared with the parent drug.
Moreover all the metal complexes were also tested for their ability to scavenge reactive oxygen species where by MnII and CuII complexes exhibited potential to mediate anti-inflammatory response.
American Psychological Association (APA)
Arayne, Saeed& Sultana, Najma& Haroon, Urooj& Mesaik, M. Ahmed. 2009. Synthesis, Characterization, Antibacterial and Anti-Inflammatory Activities of Enoxacin Metal Complexes. Bioinorganic Chemistry and Applications،Vol. 2009, no. 2009, pp.1-6.
https://search.emarefa.net/detail/BIM-507646
Modern Language Association (MLA)
Arayne, Saeed…[et al.]. Synthesis, Characterization, Antibacterial and Anti-Inflammatory Activities of Enoxacin Metal Complexes. Bioinorganic Chemistry and Applications No. 2009 (2009), pp.1-6.
https://search.emarefa.net/detail/BIM-507646
American Medical Association (AMA)
Arayne, Saeed& Sultana, Najma& Haroon, Urooj& Mesaik, M. Ahmed. Synthesis, Characterization, Antibacterial and Anti-Inflammatory Activities of Enoxacin Metal Complexes. Bioinorganic Chemistry and Applications. 2009. Vol. 2009, no. 2009, pp.1-6.
https://search.emarefa.net/detail/BIM-507646
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-507646