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Trypanosoma cruzi : Seroprevalence Detection in Suburban Population of Santiago de Querétaro (Mexico)
Joint Authors
Briceño Álvarez, Kervin
Saldaña, Carlos
Sánchez-Moreno, Manuel
Villagrán, Elena
de Diego, José Antonio
Marín, Clotilde
Hernández-Montiel, Hebert Luís
López-Céspedes, Ángeles
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-05-03
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Medicine
Information Technology and Computer Science
Abstract EN
Objectives.
To evaluate the potential of iron-oxide dismutase excreted (SODeCRU) by T.
cruzi as the antigen fraction in the serodiagnosis of Chagas disease and compile new epidemiological data on the seroprevalence of this disease in the suburban population of the city of Santiago de Querétaro (Mexico).
Design and Methods.
258 human sera were analyzed by the techniques of ELISA and Western blot and using the homogenate and the SODeCRU.
Results.
A total of 31 sera were positive against ELISA/SODeCRU (12.4%), while 30 sera proved positive by WB/SODeCRU (11.6%).
The comparison between the technique of ELISA and WB showed a sensitivity of 93%, and a specificity of 99%.
The positive predictive value was 93% and the negative predictive value was 99%, with a Kappa (κ) value of 1.
Conclusions.
These preliminary data reveal the degree of infection of nonrural areas of Mexico and demonstrated that SODeCRU is an antigen useful to diagnose Chagas disease.
American Psychological Association (APA)
López-Céspedes, Ángeles& Villagrán, Elena& Briceño Álvarez, Kervin& de Diego, José Antonio& Hernández-Montiel, Hebert Luís& Saldaña, Carlos…[et al.]. 2012. Trypanosoma cruzi : Seroprevalence Detection in Suburban Population of Santiago de Querétaro (Mexico). The Scientific World Journal،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-507648
Modern Language Association (MLA)
López-Céspedes, Ángeles…[et al.]. Trypanosoma cruzi : Seroprevalence Detection in Suburban Population of Santiago de Querétaro (Mexico). The Scientific World Journal No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-507648
American Medical Association (AMA)
López-Céspedes, Ángeles& Villagrán, Elena& Briceño Álvarez, Kervin& de Diego, José Antonio& Hernández-Montiel, Hebert Luís& Saldaña, Carlos…[et al.]. Trypanosoma cruzi : Seroprevalence Detection in Suburban Population of Santiago de Querétaro (Mexico). The Scientific World Journal. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-507648
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-507648