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A Presentation of Cerebritis Secondary to Granulomatosis with Polyangiitis (Wegener)
Joint Authors
Norman, James
Taylor, Timothy
Pande, Ira
Gran, Bruno
Source
Case Reports in Neurological Medicine
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-05-12
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Neurological manifestations of GPA are common, most frequently as a peripheral neuropathy.
Cerebritis as a principal presentation is extremely rare.
We report a patient who presented with subacute progression of ataxia, confusion, and vacant episodes.
An MRI of her brain showed bilateral signal abnormalities in the cingulate and superior sagittal gyrus while a staging CT revealed a mass in the right upper lobe of the patient’s lung with a satellite nodule.
C-ANCA antibodies specific for PR3 at high titres were positive and a diagnosis of GPA was made.
The patient was commenced on intravenous methylprednisolone followed by cyclophosphamide and responded well to treatment.
GPA is a rare and treatable differential diagnosis for confused patients with acute or subacute neurological features and unusual MRI findings.
American Psychological Association (APA)
Norman, James& Pande, Ira& Taylor, Timothy& Gran, Bruno. 2014. A Presentation of Cerebritis Secondary to Granulomatosis with Polyangiitis (Wegener). Case Reports in Neurological Medicine،Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-507678
Modern Language Association (MLA)
Norman, James…[et al.]. A Presentation of Cerebritis Secondary to Granulomatosis with Polyangiitis (Wegener). Case Reports in Neurological Medicine No. 2014 (2014), pp.1-5.
https://search.emarefa.net/detail/BIM-507678
American Medical Association (AMA)
Norman, James& Pande, Ira& Taylor, Timothy& Gran, Bruno. A Presentation of Cerebritis Secondary to Granulomatosis with Polyangiitis (Wegener). Case Reports in Neurological Medicine. 2014. Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-507678
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-507678