Elevated Serum C-Reactive Protein and Markers of Sleep Disordered Breathing
Joint Authors
Zhang, Ruoxin
Shankar, Anoop
Wiener, R. Constance
Source
International Journal of Vascular Medicine
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-02-19
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Background.
Previous studies indicated sleep-disordered breathing (SDB) is associated with cardiovascular disease (CVD).
Systemic inflammation is recognized as a risk factor for CVD.
Studies examining SDB and inflammation are limited.
Methods.
We studied sleep duration, snoring, snorting, and daytime sleepiness, and an additive SDB score.
The main outcome was a C-reactive protein (CRP) of >1 mg/dL.
Results.
Snoring, snorting, daytime sleepiness, and sleeping >7 or <7 hours, and the additive score were significantly associated with high CRP.
The additive score was not associated in men but moderately associated in women in a multivariable model adjusting for age, gender, race/ethnicity, education, smoking, hypertension, alcohol intake, physical activity, body mass index, depression, diabetes, hypertension, and total cholesterol (P-interaction =0.42).
For race/ethnicity, the association was strongest in Mexican Americans/others, modest in Non-Hispanic whites, and absent in Non-Hispanic blacks (P-interaction =0.07).
Conclusions.
The association between SDB and high CRP was present mainly in women and Mexican Americans, implying SDB has a residual, independent association with inflammation after controlling for lifestyle and metabolic risk factors like BMI, physical activity, depression, diabetes, and cholesterol.
American Psychological Association (APA)
Wiener, R. Constance& Zhang, Ruoxin& Shankar, Anoop. 2012. Elevated Serum C-Reactive Protein and Markers of Sleep Disordered Breathing. International Journal of Vascular Medicine،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-507686
Modern Language Association (MLA)
Wiener, R. Constance…[et al.]. Elevated Serum C-Reactive Protein and Markers of Sleep Disordered Breathing. International Journal of Vascular Medicine No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-507686
American Medical Association (AMA)
Wiener, R. Constance& Zhang, Ruoxin& Shankar, Anoop. Elevated Serum C-Reactive Protein and Markers of Sleep Disordered Breathing. International Journal of Vascular Medicine. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-507686
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-507686