NAFLD, Estrogens, and Physical Exercise : The Animal Model
Joint Authors
Pighon, Abdolnaser
Lavoie, Jean Marc
Source
Journal of Nutrition and Metabolism
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-08-10
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
One segment of the population that is particularly inclined to liver fat accumulation is postmenopausal women.
Although nonalcoholic hepatic steatosis is more common in men than in women, after menopause there is a reversal in gender distribution.
At the present time, weight loss and exercise are regarded as first line treatments for NAFLD in postmenopausal women, as it is the case for the management of metabolic syndrome.
In recent years, there has been substantial evidence coming mostly from the use of the animal model, that indeed estrogens withdrawal is associated with modifications of molecular markers favouring the activity of metabolic pathways ultimately leading to liver fat accumulation.
In addition, the use of the animal model has provided physiological and molecular evidence that exercise training provides estrogens-like protective effects on liver fat accumulation and its consequences.
The purpose of the present paper is to present information relative to the development of a state of NAFLD resulting from the absence of estrogens and the role of exercise training, emphasizing on the contribution of the animal model on these issues.
American Psychological Association (APA)
Lavoie, Jean Marc& Pighon, Abdolnaser. 2011. NAFLD, Estrogens, and Physical Exercise : The Animal Model. Journal of Nutrition and Metabolism،Vol. 2012, no. 2012, pp.1-13.
https://search.emarefa.net/detail/BIM-507714
Modern Language Association (MLA)
Lavoie, Jean Marc& Pighon, Abdolnaser. NAFLD, Estrogens, and Physical Exercise : The Animal Model. Journal of Nutrition and Metabolism No. 2012 (2012), pp.1-13.
https://search.emarefa.net/detail/BIM-507714
American Medical Association (AMA)
Lavoie, Jean Marc& Pighon, Abdolnaser. NAFLD, Estrogens, and Physical Exercise : The Animal Model. Journal of Nutrition and Metabolism. 2011. Vol. 2012, no. 2012, pp.1-13.
https://search.emarefa.net/detail/BIM-507714
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-507714