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Combination Drug Delivery Approaches in Metastatic Breast Cancer
Joint Authors
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-17, 17 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-04-26
Country of Publication
Egypt
No. of Pages
17
Main Subjects
Abstract EN
Disseminated metastatic breast cancer needs aggressive treatment due to its reduced response to anticancer treatment and hence low survival and quality of life.
Although in theory a combination drug therapy has advantages over single-agent therapy, no appreciable survival enhancement is generally reported whereas increased toxicity is frequently seen in combination treatment especially in chemotherapy.
Currently used combination treatments in metastatic breast cancer will be discussed with their challenges leading to the introduction of novel combination anticancer drug delivery systems that aim to overcome these challenges.
Widely studied drug delivery systems such as liposomes, dendrimers, polymeric nanoparticles, and water-soluble polymers can concurrently carry multiple anticancer drugs in one platform.
These carriers can provide improved target specificity achieved by passive and/or active targeting mechanisms.
American Psychological Association (APA)
Lee, Jun H.& Nan, Anjan. 2012. Combination Drug Delivery Approaches in Metastatic Breast Cancer. Journal of Drug Delivery،Vol. 2012, no. 2012, pp.1-17.
https://search.emarefa.net/detail/BIM-507770
Modern Language Association (MLA)
Lee, Jun H.& Nan, Anjan. Combination Drug Delivery Approaches in Metastatic Breast Cancer. Journal of Drug Delivery No. 2012 (2012), pp.1-17.
https://search.emarefa.net/detail/BIM-507770
American Medical Association (AMA)
Lee, Jun H.& Nan, Anjan. Combination Drug Delivery Approaches in Metastatic Breast Cancer. Journal of Drug Delivery. 2012. Vol. 2012, no. 2012, pp.1-17.
https://search.emarefa.net/detail/BIM-507770
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-507770