Serum Adiponectin, Resistin, and Circulating Soluble Receptor for Advanced Glycation End Products in Colectomy Patients
Joint Authors
Asgeirsson, Theodor
Zhang, Sen
Resau, James H.
Dujovny, Nadav
Khoo, Sok Kean
Senagore, Anthony J.
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-09-07
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Aim.
Surgical trauma and associated complications are frequently related to physiological stress during colectomy.
This study evaluated the response of adiponectin, resistin, and circulating soluble receptor for advanced glycation end products (sRAGE) in colectomy patients with or without an enhanced recovery protocol.
Method.
Serum samples were collected from 44 colectomy patients at 3 timframes.
The surgical procedures were laparoscopic (LAP), hand-assisted laparoscopic (HALS), or open colectomy (OPEN).
Adiponectin, resistin, and sRAGE levels were determined by ELISA.
Repeated measures ANOVA was applied and P values < 0.05 were considered significant.
Results.
A total of 132 (44 × 3) sera were used for analysis.
Levels of adiponectin was significantly decreased between PREOP and POD3 (P<0.001).
Conversely, concentrations of resistin significantly increased from PREOP to POD1 and returned to baseline value by POD3 (P<0.001).
Serum sRAGE levels were significantly higher in LAP in comparison with HALS (P=0.004) and OPEN (P<0.001).
sRAGE levels were significantly higher in sera of patients that underwent ERP (P<0.001).
Conclusions.
Serum adiponectin, resistin, and sRAGE have the potential to develop into a panel of stress markers.
Higher sRAGE levels in sera of LAP and ERP patients may be indicative of a protective and syngeristic role for colectomy recovery.
American Psychological Association (APA)
Asgeirsson, Theodor& Zhang, Sen& Khoo, Sok Kean& Resau, James H.& Dujovny, Nadav& Senagore, Anthony J.. 2011. Serum Adiponectin, Resistin, and Circulating Soluble Receptor for Advanced Glycation End Products in Colectomy Patients. Mediators of Inflammation،Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-507890
Modern Language Association (MLA)
Asgeirsson, Theodor…[et al.]. Serum Adiponectin, Resistin, and Circulating Soluble Receptor for Advanced Glycation End Products in Colectomy Patients. Mediators of Inflammation No. 2011 (2011), pp.1-6.
https://search.emarefa.net/detail/BIM-507890
American Medical Association (AMA)
Asgeirsson, Theodor& Zhang, Sen& Khoo, Sok Kean& Resau, James H.& Dujovny, Nadav& Senagore, Anthony J.. Serum Adiponectin, Resistin, and Circulating Soluble Receptor for Advanced Glycation End Products in Colectomy Patients. Mediators of Inflammation. 2011. Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-507890
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-507890