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Environmental Effects on Fractional Exhaled Nitric Oxide in Allergic Children
Joint Authors
Ferrante, Giuliana
Viegi, Giovanni
Malizia, Velia
Cibella, Fabio
La Grutta, Stefania
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-11-17
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Fractional exhaled nitric oxide (FeNO) is a non-invasive marker of airway inflammation in asthma and respiratory allergy.
Environmental factors, especially indoor and outdoor air quality, may play an important role in triggering acute exacerbations of respiratory symptoms.
The authors have reviewed the literature reporting effects of outdoor and indoor pollutants on FeNO in children.
Although the findings are not consistent, urban and industrial pollution—mainly particles (PM2.5 and PM10), nitrogen dioxide (NO2), and sulfur dioxide (SO2)—as well as formaldehyde and electric baseboard heating have been shown to increase FeNO, whilst ozone (O3) tends to decrease it.
Among children exposed to Environmental Tobacco Smoke (ETS) with a genetic polymorphisms in nitric oxide synthase genes (NOS), a higher nicotine exposure was associated with lower FeNO levels.
Finally, although more studies are needed in order to better investigate the effect of gene and environment interactions which may affect the interpretation of FeNO values in the management of children with asthma, clinicians are recommended to consider environmental exposures when taking medical histories for asthma and respiratory allergy.
Further research is also needed to assess the effects of remedial interventions aimed at reducing/abating environmental exposures in asthmatic/allergic patients.
American Psychological Association (APA)
La Grutta, Stefania& Ferrante, Giuliana& Malizia, Velia& Cibella, Fabio& Viegi, Giovanni. 2011. Environmental Effects on Fractional Exhaled Nitric Oxide in Allergic Children. Journal of Allergy،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-507903
Modern Language Association (MLA)
La Grutta, Stefania…[et al.]. Environmental Effects on Fractional Exhaled Nitric Oxide in Allergic Children. Journal of Allergy No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-507903
American Medical Association (AMA)
La Grutta, Stefania& Ferrante, Giuliana& Malizia, Velia& Cibella, Fabio& Viegi, Giovanni. Environmental Effects on Fractional Exhaled Nitric Oxide in Allergic Children. Journal of Allergy. 2011. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-507903
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-507903