Salvage of Failed Local and Regional Flaps with Porcine Urinary Bladder Extracellular Matrix Aided Tissue Regeneration
Joint Authors
VandeGriend, Zachary P.
Zuliani, Giancarlo F.
Lin, Ho-Sheng
Kruper, Gregory J.
Source
Case Reports in Otolaryngology
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-09-26
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Local and regional flap failure can be a major complication in head and neck surgery, which continue to be prevalent for a number of reasons including poor flap design, improper surgical technique, and poor tissue vascularity.
Dealing with these failures can be quite difficult.
Surgical debridement, flap revisions, and complex wound regimens are necessitated to reestablish appropriate tissue coverage.
Traditional use of wet to dry dressing to enable proper wound granulation and possible closure with additional flaps or skin grafts is a laborious process.
Such treatments place great time burdens on the patient, physicians, and nurses.
Because the face and neck possess a complex three-dimensional topography, wound dressings are inherently complex to design and change.
Many patients also require postoperative treatments such as radiation and chemotherapy to treat aggressive malignancies, and delay in wound healing leads to a delay in adjuvant treatment.
Recently, advances in regenerative medicine, specifically xenogeneic extracellular matrix compounds, have been shown to promote tissue growth while limiting scar tissue formation (Badylak 2004).
To our knowledge, this paper is the first case series using the porcine extracellular matrix bioscaffold (MatriStem ACell, Columbia, MD, USA) to salvage flaps with extensive wound breakdown on the face and neck.
American Psychological Association (APA)
Kruper, Gregory J.& VandeGriend, Zachary P.& Lin, Ho-Sheng& Zuliani, Giancarlo F.. 2013. Salvage of Failed Local and Regional Flaps with Porcine Urinary Bladder Extracellular Matrix Aided Tissue Regeneration. Case Reports in Otolaryngology،Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-507931
Modern Language Association (MLA)
Kruper, Gregory J.…[et al.]. Salvage of Failed Local and Regional Flaps with Porcine Urinary Bladder Extracellular Matrix Aided Tissue Regeneration. Case Reports in Otolaryngology No. 2013 (2013), pp.1-5.
https://search.emarefa.net/detail/BIM-507931
American Medical Association (AMA)
Kruper, Gregory J.& VandeGriend, Zachary P.& Lin, Ho-Sheng& Zuliani, Giancarlo F.. Salvage of Failed Local and Regional Flaps with Porcine Urinary Bladder Extracellular Matrix Aided Tissue Regeneration. Case Reports in Otolaryngology. 2013. Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-507931
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-507931