Salvage of Failed Local and Regional Flaps with Porcine Urinary Bladder Extracellular Matrix Aided Tissue Regeneration

Joint Authors

VandeGriend, Zachary P.
Zuliani, Giancarlo F.
Lin, Ho-Sheng
Kruper, Gregory J.

Source

Case Reports in Otolaryngology

Issue

Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-5, 5 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2013-09-26

Country of Publication

Egypt

No. of Pages

5

Main Subjects

Diseases

Abstract EN

Local and regional flap failure can be a major complication in head and neck surgery, which continue to be prevalent for a number of reasons including poor flap design, improper surgical technique, and poor tissue vascularity.

Dealing with these failures can be quite difficult.

Surgical debridement, flap revisions, and complex wound regimens are necessitated to reestablish appropriate tissue coverage.

Traditional use of wet to dry dressing to enable proper wound granulation and possible closure with additional flaps or skin grafts is a laborious process.

Such treatments place great time burdens on the patient, physicians, and nurses.

Because the face and neck possess a complex three-dimensional topography, wound dressings are inherently complex to design and change.

Many patients also require postoperative treatments such as radiation and chemotherapy to treat aggressive malignancies, and delay in wound healing leads to a delay in adjuvant treatment.

Recently, advances in regenerative medicine, specifically xenogeneic extracellular matrix compounds, have been shown to promote tissue growth while limiting scar tissue formation (Badylak 2004).

To our knowledge, this paper is the first case series using the porcine extracellular matrix bioscaffold (MatriStem ACell, Columbia, MD, USA) to salvage flaps with extensive wound breakdown on the face and neck.

American Psychological Association (APA)

Kruper, Gregory J.& VandeGriend, Zachary P.& Lin, Ho-Sheng& Zuliani, Giancarlo F.. 2013. Salvage of Failed Local and Regional Flaps with Porcine Urinary Bladder Extracellular Matrix Aided Tissue Regeneration. Case Reports in Otolaryngology،Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-507931

Modern Language Association (MLA)

Kruper, Gregory J.…[et al.]. Salvage of Failed Local and Regional Flaps with Porcine Urinary Bladder Extracellular Matrix Aided Tissue Regeneration. Case Reports in Otolaryngology No. 2013 (2013), pp.1-5.
https://search.emarefa.net/detail/BIM-507931

American Medical Association (AMA)

Kruper, Gregory J.& VandeGriend, Zachary P.& Lin, Ho-Sheng& Zuliani, Giancarlo F.. Salvage of Failed Local and Regional Flaps with Porcine Urinary Bladder Extracellular Matrix Aided Tissue Regeneration. Case Reports in Otolaryngology. 2013. Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-507931

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-507931