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Outcome and Prognostic Indicators of Patients with Hematopoietic Stem Cell Transplants Admitted to the Intensive Care Unit
Joint Authors
Territo, Mary
Weigt, S. Sam
Keane, Michael P.
Belperio, John A.
Huynh, Thanh N.
Source
Issue
Vol. 2009, Issue 2009 (31 Dec. 2009), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2009-09-15
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
The prognosis of patients with hematopoietic stem cell transplants (HSCTs) who require admission to the intensive care unit (ICU) has been regarded as extremely poor.
We sought to re-evaluate recent outcomes and predictive factors in a retrospective cohort study.
Among the 605 adult patients that received an HSCT between 2001 and 2006, 154 required admission to the ICU.
Of these, 47% were discharged from the ICU, 36% were discharged from the hospital, and 19% survived 6 months.
Allogeneic transplant, mechanical ventilation, vasopressor-use, and neutropenia were each associated with increased mortality, and the mortality of patients with all four characteristics was 100%.
Hemodialysis was also associated with increased mortality in a Kaplan-Meier analysis but did not appear important in a multivariate tree analysis.
A final Cox model confirmed that allogeneic transplant, mechanical ventilation, and vasopressor-use were each independent risk factors for mortality in the 6 months following ICU admission.
American Psychological Association (APA)
Huynh, Thanh N.& Weigt, S. Sam& Belperio, John A.& Territo, Mary& Keane, Michael P.. 2009. Outcome and Prognostic Indicators of Patients with Hematopoietic Stem Cell Transplants Admitted to the Intensive Care Unit. Journal of Transplantation،Vol. 2009, no. 2009, pp.1-8.
https://search.emarefa.net/detail/BIM-507940
Modern Language Association (MLA)
Huynh, Thanh N.…[et al.]. Outcome and Prognostic Indicators of Patients with Hematopoietic Stem Cell Transplants Admitted to the Intensive Care Unit. Journal of Transplantation No. 2009 (2009), pp.1-8.
https://search.emarefa.net/detail/BIM-507940
American Medical Association (AMA)
Huynh, Thanh N.& Weigt, S. Sam& Belperio, John A.& Territo, Mary& Keane, Michael P.. Outcome and Prognostic Indicators of Patients with Hematopoietic Stem Cell Transplants Admitted to the Intensive Care Unit. Journal of Transplantation. 2009. Vol. 2009, no. 2009, pp.1-8.
https://search.emarefa.net/detail/BIM-507940
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-507940