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Prolonged Survival of a Refractory Acute Myeloid Leukemia Patient after a Third Hematopoietic Stem Cell Transplantation with Umbilical Cord Blood following a Second Relapse
Joint Authors
Kurita, Naoki
Chiba, Shigeru
Seki, Masanori
Lee, Suk-young
Maie, Koichiro
Suzukawa, Kazumi
Yokoyama, Yasuhisa
Hasegawa, Yuichi
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-02-09
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
Although hematopoietic stem cell transplantation (HSCT) has been considered to be the only way for potential cure of relapsed acute myeloid leukemia (AML), there has been no report on a third HSCT in patients with multiple relapsed AML.
Here, we report a case of 53-year-old female who received a successful third allogeneic HSCT after relapse of AML following a second allogeneic HSCT.
She was treated with a toxicity reduced conditioning regimen and received direct intrabone cord blood transplantation (CBT) using a single unit of 5/6 HLA-matched cord blood as a graft source.
Graft-versus-host disease prophylaxis was performed with a single agent of tacrolimus to increase graft-versus-leukemia effect.
She is in remission for 8 months since the direct intrabone CBT.
This report highlights not only the importance of individually adjusted approach but also the need for further investigation on the role of HSCT as a treatment modality in patients with refractory or multiple relapsed AML.
American Psychological Association (APA)
Lee, Suk-young& Kurita, Naoki& Maie, Koichiro& Seki, Masanori& Yokoyama, Yasuhisa& Suzukawa, Kazumi…[et al.]. 2014. Prolonged Survival of a Refractory Acute Myeloid Leukemia Patient after a Third Hematopoietic Stem Cell Transplantation with Umbilical Cord Blood following a Second Relapse. Case Reports in Hematology،Vol. 2014, no. 2014, pp.1-3.
https://search.emarefa.net/detail/BIM-508097
Modern Language Association (MLA)
Lee, Suk-young…[et al.]. Prolonged Survival of a Refractory Acute Myeloid Leukemia Patient after a Third Hematopoietic Stem Cell Transplantation with Umbilical Cord Blood following a Second Relapse. Case Reports in Hematology No. 2014 (2014), pp.1-3.
https://search.emarefa.net/detail/BIM-508097
American Medical Association (AMA)
Lee, Suk-young& Kurita, Naoki& Maie, Koichiro& Seki, Masanori& Yokoyama, Yasuhisa& Suzukawa, Kazumi…[et al.]. Prolonged Survival of a Refractory Acute Myeloid Leukemia Patient after a Third Hematopoietic Stem Cell Transplantation with Umbilical Cord Blood following a Second Relapse. Case Reports in Hematology. 2014. Vol. 2014, no. 2014, pp.1-3.
https://search.emarefa.net/detail/BIM-508097
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-508097