Blood Loss and Massive Transfusion in Patients Undergoing Major Oncological Surgery : What Do We Know?
Joint Authors
Gottumukkala, Vijaya
Cata, Juan P.
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-05-13
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Patients with solid malignancies who were not candidates for tumor resections in the past are now presenting for extensive oncological resections.
Cancer patients are at risk for thromboembolic complications due to an underlying hypercoagulable state; however, some patients may have an increased risk for bleeding due to the effects of chemotherapy, the administration of anticoagulant drugs, tumor-related fibrinolysis, tumor location, tumor vascularity, and extent of disease.
A common potential complication of all complex oncological surgeries is massive intra- and postoperative hemorrhage and the subsequent risk for massive blood transfusion.
This can be anticipated or unexpected.
Several surgical and anesthesia interventions including preoperative tumor embolization, major vessel occlusion, hemodynamic manipulation, and perioperative antifibrinolytic therapy have been used to prevent or control blood loss with varying success.
The exact incidence of massive blood transfusion in oncological surgery is largely unknown and/or underreported.
The current literature mostly consists of purely descriptive observational studies.
Thus, recommendation regarding specific perioperative intervention cannot be made at this point, and more research is warranted.
American Psychological Association (APA)
Cata, Juan P.& Gottumukkala, Vijaya. 2012. Blood Loss and Massive Transfusion in Patients Undergoing Major Oncological Surgery : What Do We Know?. ISRN Anesthesiology،Vol. 2012, no. 2012, pp.1-11.
https://search.emarefa.net/detail/BIM-508110
Modern Language Association (MLA)
Cata, Juan P.& Gottumukkala, Vijaya. Blood Loss and Massive Transfusion in Patients Undergoing Major Oncological Surgery : What Do We Know?. ISRN Anesthesiology No. 2012 (2012), pp.1-11.
https://search.emarefa.net/detail/BIM-508110
American Medical Association (AMA)
Cata, Juan P.& Gottumukkala, Vijaya. Blood Loss and Massive Transfusion in Patients Undergoing Major Oncological Surgery : What Do We Know?. ISRN Anesthesiology. 2012. Vol. 2012, no. 2012, pp.1-11.
https://search.emarefa.net/detail/BIM-508110
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-508110