Hemodynamic Correlates of Late Systolic Flow Velocity Augmentation in the Carotid Artery
Joint Authors
Heffernan, Kevin S.
Augustine, Jacqueline A.
Lefferts, Wesley K.
Source
International Journal of Hypertension
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-11-14
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Background.
The contour of the common carotid artery (CCA) blood flow velocity waveform changes with age; CCA flow velocity increases during late systole, and this may contribute to cerebrovascular disease.
Late systolic flow velocity augmentation can be quantified using the flow augmentation index (FAIx).
We examined hemodynamic correlates of FAIx to gain insight into determinants of CCA flow patterns.
Methods.
CCA Doppler ultrasound and wave intensity analysis (WIA) were used to assess regional hemodynamics in 18 young healthy men (age 22 ± 1 years).
Forward waves (W1) and backward waves (negative area, NA) were measured and used to calculate the reflection index (NA/W1 = RIx).
Additional parameters included W2 which is a forward travelling expansion/decompression wave of myocardial origin that produces suction, CCA single-point pulse wave velocity (PWV) as a measure of arterial stiffness, and CCA pressure augmentation index (AIx).
Results.
Primary correlates of FAIx included W2 (r = -0.52, P<0.05), logRIx (r = 0.56, P<0.05), and AIx (r = 0.60, P<0.05).
FAIx was not associated with CCA stiffness (P>0.05).
Conclusions.
FAIx is a complex ventricular-vascular coupling parameter that is associated with both increased expansion wave magnitude (increased suction from the left ventricle) and increased pressure from wave reflections.
American Psychological Association (APA)
Heffernan, Kevin S.& Lefferts, Wesley K.& Augustine, Jacqueline A.. 2013. Hemodynamic Correlates of Late Systolic Flow Velocity Augmentation in the Carotid Artery. International Journal of Hypertension،Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-508230
Modern Language Association (MLA)
Heffernan, Kevin S.…[et al.]. Hemodynamic Correlates of Late Systolic Flow Velocity Augmentation in the Carotid Artery. International Journal of Hypertension No. 2013 (2013), pp.1-7.
https://search.emarefa.net/detail/BIM-508230
American Medical Association (AMA)
Heffernan, Kevin S.& Lefferts, Wesley K.& Augustine, Jacqueline A.. Hemodynamic Correlates of Late Systolic Flow Velocity Augmentation in the Carotid Artery. International Journal of Hypertension. 2013. Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-508230
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-508230