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Biomedical Properties of a Natural Dietary Plant Metabolite, Zerumbone, in Cancer Therapy and Chemoprevention Trials
Joint Authors
How, Chee Wun
Rahman, Heshu Sulaiman
Chartrand, Max Stanley
Othman, Hemn Hassan
Namvar, Farideh
Rasedee, Abdullah
Abdul, Ahmad Bustamam
Yeap, Swee Keong
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-20, 20 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-06-15
Country of Publication
Egypt
No. of Pages
20
Main Subjects
Abstract EN
Zerumbone (ZER) is a naturally occurring dietary compound, present in many natural foods consumed today.
The compound derived from several plant species of the Zingiberaceae family that has been found to possess multiple biomedical properties, such as antiproliferative, antioxidant, anti-inflammatory, and anticancer activities.
However, evidence of efficacy is sparse, pointing to the need for a more systematic review for assessing scientific evidence to support therapeutic claims made for ZER and to identify future research needs.
This review provides an updated overview of in vitro and in vivo investigations of ZER, its cancer chemopreventive properties, and mechanisms of action.
Therapeutic effects of ZER were found to be scientifically plausible and could be explained partially by in vivo and in vitro pharmacological activities.
Much of the research outlined in this paper will serve as a foundation to explain ZER anticancer bioactivity, which will open the door for the development of strategies in the treatment of malignancies using ZER.
American Psychological Association (APA)
Rahman, Heshu Sulaiman& Rasedee, Abdullah& Yeap, Swee Keong& Othman, Hemn Hassan& Chartrand, Max Stanley& Namvar, Farideh…[et al.]. 2014. Biomedical Properties of a Natural Dietary Plant Metabolite, Zerumbone, in Cancer Therapy and Chemoprevention Trials. BioMed Research International،Vol. 2014, no. 2014, pp.1-20.
https://search.emarefa.net/detail/BIM-508251
Modern Language Association (MLA)
Rahman, Heshu Sulaiman…[et al.]. Biomedical Properties of a Natural Dietary Plant Metabolite, Zerumbone, in Cancer Therapy and Chemoprevention Trials. BioMed Research International No. 2014 (2014), pp.1-20.
https://search.emarefa.net/detail/BIM-508251
American Medical Association (AMA)
Rahman, Heshu Sulaiman& Rasedee, Abdullah& Yeap, Swee Keong& Othman, Hemn Hassan& Chartrand, Max Stanley& Namvar, Farideh…[et al.]. Biomedical Properties of a Natural Dietary Plant Metabolite, Zerumbone, in Cancer Therapy and Chemoprevention Trials. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-20.
https://search.emarefa.net/detail/BIM-508251
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-508251