Comparison of Five Parathyroid Scintigraphic Protocols
Joint Authors
Schildt, Jukka
Ahonen, Aapo
Eskola, Hannu
Tunninen, Virpi
Varjo, Pekka
Kauppinen, Tomi
Lisinen, Irina
Holm, Anu
Seppänen, Marko
Source
International Journal of Molecular Imaging
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-01-21
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Objectives.
We compared five parathyroid scintigraphy protocols in patients with primary (pHPT) and secondary hyperparathyroidism (sHPT) and studied the interobserver agreement.
The dual-tracer method (T99mc-sestamibi/123I) was used with three acquisition techniques (parallel-hole planar, pinhole planar, and SPECT/CT).
The single-tracer method (T99mc-sestamibi) was used with two acquisition techniques (double-phase parallel-hole planar, and SPECT/CT).
Thus five protocols were used, resulting in five sets of images.
Materials and Methods.
Image sets of 51 patients were retrospectively graded by four experienced nuclear medicine physicians.
The final study group consisted of 24 patients (21 pHPT, 3 sHPT) who had been operated upon.
Surgical and histopathologic findings were used as the standard of comparison.
Results.
Thirty abnormal parathyroid glands were found in 24 patients.
The sensitivities of the dual-tracer method (76.7–80.0%) were similar (P=1.0).
The sensitivities of the single-tracer method (13.3–31.6%) were similar (P=0.625).
All differences in sensitivity between these two methods were statistically significant (P<0.012).
The interobserver agreement was good.
Conclusion.
This study indicates that any dual-tracer protocol with T99mc-sestamibi and 123I is superior for enlarged parathyroid gland localization when compared with single-tracer protocols using T99mc-sestamibi alone.
The parathyroid scintigraphy was found to be independent of the reporter.
American Psychological Association (APA)
Tunninen, Virpi& Varjo, Pekka& Schildt, Jukka& Ahonen, Aapo& Kauppinen, Tomi& Lisinen, Irina…[et al.]. 2013. Comparison of Five Parathyroid Scintigraphic Protocols. International Journal of Molecular Imaging،Vol. 2013, no. 2013, pp.1-12.
https://search.emarefa.net/detail/BIM-508293
Modern Language Association (MLA)
Tunninen, Virpi…[et al.]. Comparison of Five Parathyroid Scintigraphic Protocols. International Journal of Molecular Imaging No. 2013 (2013), pp.1-12.
https://search.emarefa.net/detail/BIM-508293
American Medical Association (AMA)
Tunninen, Virpi& Varjo, Pekka& Schildt, Jukka& Ahonen, Aapo& Kauppinen, Tomi& Lisinen, Irina…[et al.]. Comparison of Five Parathyroid Scintigraphic Protocols. International Journal of Molecular Imaging. 2013. Vol. 2013, no. 2013, pp.1-12.
https://search.emarefa.net/detail/BIM-508293
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-508293