Notch Signaling in T-Cell Development and T-ALL
Joint Authors
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-01-23
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
The Notch signaling pathway is an evolutionarily conserved cell signaling system present in most multicellular organisms, as it controls cell fate specification by regulating cell proliferation, differentiation, apoptosis, and survival.
Regulation of the Notch signaling pathway can be achieved at multiple levels.
Notch proteins are involved in lineage fate decisions in a variety of tissues in various species.
Notch is essential for T lineage cell differentiation including T versus B and αβ versus γδ lineage specification.
In this paper, we discuss Notch signaling in normal T-cell maturation and differentiation as well as in T-cell acute lymphoblastic lymphoma/leukemia.
American Psychological Association (APA)
Li, Xiaoyu& von Boehmer, Harald. 2011. Notch Signaling in T-Cell Development and T-ALL. ISRN Hematology،Vol. 2011, no. 2011, pp.1-9.
https://search.emarefa.net/detail/BIM-508338
Modern Language Association (MLA)
Li, Xiaoyu& von Boehmer, Harald. Notch Signaling in T-Cell Development and T-ALL. ISRN Hematology No. 2011 (2011), pp.1-9.
https://search.emarefa.net/detail/BIM-508338
American Medical Association (AMA)
Li, Xiaoyu& von Boehmer, Harald. Notch Signaling in T-Cell Development and T-ALL. ISRN Hematology. 2011. Vol. 2011, no. 2011, pp.1-9.
https://search.emarefa.net/detail/BIM-508338
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-508338