Cell Microenvironment Engineering and Monitoring for Tissue Engineering and Regenerative Medicine : The Recent Advances
Joint Authors
Vrana, Nihal Engin
Ndreu-Halili, Albana
Barthes, Julien
Hindié, Mathilde
Hasan, Anwarul
Özçelik, Hayriye
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-18, 18 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-07-17
Country of Publication
Egypt
No. of Pages
18
Main Subjects
Abstract EN
In tissue engineering and regenerative medicine, the conditions in the immediate vicinity of the cells have a direct effect on cells’ behaviour and subsequently on clinical outcomes.
Physical, chemical, and biological control of cell microenvironment are of crucial importance for the ability to direct and control cell behaviour in 3-dimensional tissue engineering scaffolds spatially and temporally.
In this review, we will focus on the different aspects of cell microenvironment such as surface micro-, nanotopography, extracellular matrix composition and distribution, controlled release of soluble factors, and mechanical stress/strain conditions and how these aspects and their interactions can be used to achieve a higher degree of control over cellular activities.
The effect of these parameters on the cellular behaviour within tissue engineering context is discussed and how these parameters are used to develop engineered tissues is elaborated.
Also, recent techniques developed for the monitoring of the cell microenvironment in vitro and in vivo are reviewed, together with recent tissue engineering applications where the control of cell microenvironment has been exploited.
Cell microenvironment engineering and monitoring are crucial parts of tissue engineering efforts and systems which utilize different components of the cell microenvironment simultaneously can provide more functional engineered tissues in the near future.
American Psychological Association (APA)
Barthes, Julien& Özçelik, Hayriye& Hindié, Mathilde& Ndreu-Halili, Albana& Hasan, Anwarul& Vrana, Nihal Engin. 2014. Cell Microenvironment Engineering and Monitoring for Tissue Engineering and Regenerative Medicine : The Recent Advances. BioMed Research International،Vol. 2014, no. 2014, pp.1-18.
https://search.emarefa.net/detail/BIM-508361
Modern Language Association (MLA)
Barthes, Julien…[et al.]. Cell Microenvironment Engineering and Monitoring for Tissue Engineering and Regenerative Medicine : The Recent Advances. BioMed Research International No. 2014 (2014), pp.1-18.
https://search.emarefa.net/detail/BIM-508361
American Medical Association (AMA)
Barthes, Julien& Özçelik, Hayriye& Hindié, Mathilde& Ndreu-Halili, Albana& Hasan, Anwarul& Vrana, Nihal Engin. Cell Microenvironment Engineering and Monitoring for Tissue Engineering and Regenerative Medicine : The Recent Advances. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-18.
https://search.emarefa.net/detail/BIM-508361
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-508361