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Hypertransfusion Therapy in Sickle Cell Disease in Nigeria
Joint Authors
Adewoyin, Ademola Samson
Obieche, Jude Chike
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-08-07
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Introduction.
Hypertransfusion refers to chronic blood transfusion therapy aimed at ameliorating disease complications in various haemopathies particularly the haemoglobinopathies.
In sickle cell disease, hypertransfusion is aimed at maintaining patient’s haemoglobin level at 10 to 11 g/dL using haemoglobin AA blood and its resultant dilutional effect on sickle haemoglobin is sustained by intermittent long-term transfusions.
Aim and Objective.
This paper highlights hypertransfusion and its privileged position as a secondary measure in prevention and treatment of sickle cell disease, especially in the Nigerian context.
Materials and Methods.
Relevant literatures were searched on PubMed, Google Scholar and standard texts in haematology and transfusion medicine.
Keywords used in the search are hypertransfusion, sickle cell disease, chronic transfusion, and Nigeria.
Literatures gathered were reviewed, summarized, and presented in this paper.
Result.
Immense clinical benefit is associated with hypertransfusion therapy including prevention of stroke and amelioration of severe sickle cell disease especially in transplant ineligible patients.
Careful patient selections, appropriate blood component, and prevention of transfusion hazards as well as oversight function of an experienced haematologist are pertinent to a successful hypertransfusion therapy.
Conclusion.
Improved knowledge of the benefits and practice of hypertransfusion will effectively translate into improved health status even among Nigerian sickle cell disease patients.
American Psychological Association (APA)
Adewoyin, Ademola Samson& Obieche, Jude Chike. 2014. Hypertransfusion Therapy in Sickle Cell Disease in Nigeria. Advances in Hematology،Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-508414
Modern Language Association (MLA)
Adewoyin, Ademola Samson& Obieche, Jude Chike. Hypertransfusion Therapy in Sickle Cell Disease in Nigeria. Advances in Hematology No. 2014 (2014), pp.1-8.
https://search.emarefa.net/detail/BIM-508414
American Medical Association (AMA)
Adewoyin, Ademola Samson& Obieche, Jude Chike. Hypertransfusion Therapy in Sickle Cell Disease in Nigeria. Advances in Hematology. 2014. Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-508414
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-508414