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Digital Ischemia in Scleroderma Spectrum of Diseases
Joint Authors
Impens, Ann Julie
Phillips, Kristine
Schiopu, Elena
Source
International Journal of Rheumatology
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-08-31
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Systemic Sclerosis (Scleroderma, SSc) is a disease of unknown etiology characterized by widespread vasculopathy and extracellular matrix deposition leading to fibrosis and autoimmune processes.
Digital ischemia (digital ulcers (DUs)) is the hallmark of SSc-related vasculopathy and is characterized by endothelial dysfunction leading to intimal proliferation and thrombosis.
It happens frequently (30% of the patients each year) and it is associated with significant morbidity.
This paper summarizes the current information regarding pathogenesis, definitions, management, and exploratory therapies in DUs associated with SSc.
American Psychological Association (APA)
Schiopu, Elena& Impens, Ann Julie& Phillips, Kristine. 2010. Digital Ischemia in Scleroderma Spectrum of Diseases. International Journal of Rheumatology،Vol. 2010, no. 2010, pp.1-8.
https://search.emarefa.net/detail/BIM-508431
Modern Language Association (MLA)
Schiopu, Elena…[et al.]. Digital Ischemia in Scleroderma Spectrum of Diseases. International Journal of Rheumatology No. 2010 (2010), pp.1-8.
https://search.emarefa.net/detail/BIM-508431
American Medical Association (AMA)
Schiopu, Elena& Impens, Ann Julie& Phillips, Kristine. Digital Ischemia in Scleroderma Spectrum of Diseases. International Journal of Rheumatology. 2010. Vol. 2010, no. 2010, pp.1-8.
https://search.emarefa.net/detail/BIM-508431
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-508431