Predictors of Fracture Risk and Bone Mineral Density in Men with Prostate Cancer on Androgen Deprivation Therapy
Joint Authors
Adams-Huet, Beverley
Farukhi, Irfan M.
Delapena, Rosinda C.
Gruntmanis, Ugis
Neubecker, Katherine
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-07-28
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Decrease of bone mineral density (BMD) and fracture risk is increased in men with prostate cancer receiving androgen deprivation therapy (ADT).
We looked at possible predictors of decreased BMD and increased fracture risk in men with prostate cancer; most of whom were on ADT.
In a retrospective study, we analyzed serum, BMD, and clinical risk factors used in the Fracture Risk Assessment (FRAX) tool and others in 78 men with prostate cancer with reported height loss.
The subjects were divided in two groups: 22 men with and 56 without vertebral fractures.
17 of the 22 men with vertebral fractures on spine X-rays did not know they had a vertebral fracture.
Of those 17 men, 9 had not previously qualified for treatment based on preradiograph FRAX score calculated with BMD, and 6 based on FRAX calculated without BMD.
Performing spine films increased the predictive ability of FRAX for vertebral fracture.
Vertebral fracture was better predicted by FRAX for other osteoporotic fractures than FRAX for hip fractures.
The inclusion of BMD in FRAX calculations did not affect the predictive ability of FRAX.
The PSA level showed a positive correlation with lumbar spine BMD and accounted for about 9% of spine BMD.
American Psychological Association (APA)
Neubecker, Katherine& Adams-Huet, Beverley& Farukhi, Irfan M.& Delapena, Rosinda C.& Gruntmanis, Ugis. 2011. Predictors of Fracture Risk and Bone Mineral Density in Men with Prostate Cancer on Androgen Deprivation Therapy. Journal of Osteoporosis،Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-508509
Modern Language Association (MLA)
Neubecker, Katherine…[et al.]. Predictors of Fracture Risk and Bone Mineral Density in Men with Prostate Cancer on Androgen Deprivation Therapy. Journal of Osteoporosis No. 2011 (2011), pp.1-6.
https://search.emarefa.net/detail/BIM-508509
American Medical Association (AMA)
Neubecker, Katherine& Adams-Huet, Beverley& Farukhi, Irfan M.& Delapena, Rosinda C.& Gruntmanis, Ugis. Predictors of Fracture Risk and Bone Mineral Density in Men with Prostate Cancer on Androgen Deprivation Therapy. Journal of Osteoporosis. 2011. Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-508509
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-508509